Will anti-depressents worsen rls? I am taking effexor XR and my rls is getting worse. However, it's getting worse all years and I was on anti-depressents six months ago with no problems, also my rls was getting worse before I was on effexor xr. So I am not sure if it's my natural rls getting slowly worse or if it's the drug or a combo. Does anyone else have this going on?
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