Hi ladies, I had like 14 vials of blood drawn 1 week ago and got my results today. I am positive for C677T mutation and I have low levels of Protein S activity. I am so relieved to have more reassurance that I didn't cause my baby's death, but now I have to try to prevent it from happening again. My OB told me to start taking a 81mg aspirin daily, which I have been for over a month, but she said I probably don't need Lovenox. Probably? If ther's a chance that something will happen if I dont tale Lovenox I don't want to take that chance!! I read that with MTHFR you should take higher than average doses of folic acid but she didn't mention anything about it. I'm only taking what's in my prenatals.
Do any of you who have these conditions have any advice for me?
Yes i have MTHFR and my doctor has me on 4mg of folic acid, lovenox injections once a day and a prenatal vitamin. I also know someone else who has the exact same thing you have. She has both conditions. She has had multiple miscarriages and she is now 23 weeks pregnant. Her doctor also has her taking 4mg of folic acid, lovenox injections, and neevo DHA prenatal which is the same one i am on. That type of prenatal is specifically for MTHFR. If your body cannot break down the folic acid then this vitamin already has it broken down for you so that your body doesn't have to do it. So you might look into it. I really don't know if i have to be on all of this but my doctor told me that she doesn't want to take any chances so you might just mention it to your doctor. Happy Thanksgiving!
I am heterozygous for MTHFR. It is very common. I am taking an additional vitamin called Folbic as a precaution. It is a combo of folic acid and other B vitamins.
Did they check your homocysteine levels? It is my understanding that as long as your homocysteine levels are within normal levels, you are not affected by the MTHFR. Mine were but on the high side of normal so I am taking the Folbic as a precaution anyway.
I am compound hetero for MTHFR (one A copy and one C). Do you have one copy of the C or two? That makes a difference. I am on 5mg of folic and a baby aspirin a day (BA for the rest of my life!). I also take a B vitamin supplement because I am a vegetarian AND I read it helps with folic absorption. Doc didn't seem to care about the B though.
The three I have talked to definitely did not suggest any kind of injections as, in their experience, the extra folic and baby aspirin works while the risks of having too thin blood (injections) are not worth it. I'm sure you've heard that 40% of the population has some form of MTHFR so obviously plenty of pregnancies go perfectly even with the mutation (nice to know and take the precautions though!). One doc also said he has never seen MTHFR lead to a stillbirth, only early miscarriages. That didn't make me feel any better about the future but it means this did not cause my 27 week stillbirth.
I agree it depends on what kind of MTHFR you have, whether your homocysteine levels are high, and how the Protein S factors in (I don't have that). I think you need to ask your doc more specific questions, get a second opinion, or switch doctors until you get one who can be really specific with you and convince you to trust them. At some point you either give over to trusting your doc or you need to get a new one. That's how I feel.
Also, don't trust everything you read on the internet! It will drive you crazy because it is so conflicting! Do some "real" research or call experts until you get "real" answers. There will always be someone out there doing more or less than you...making you second guess yourself...that's why a doc you trust is essential. Good luck!
Thank you ladies for the wealth of information on the subject. I called my OB and asked her about folic acid and the Neevo prenatals, she never even heard of Neevo since it's pretty new. She gave me a prescription for both and thanked me for informing her about Neevo.I'll be seeinf MFM to determine if I need Lovenox or not.
I will just have to pray everyday that this little one arrives healthy and screaming.
Hi, I'm not pregnant but I tested positive for MTHFR and C677T and I was classified as Homozygous. However, my perinatologist suggested I get a test to check the homocysteine levels in my blood. High homocysteine levels can cause your blood to be thicker and that's what can cause the heart disease stuff and the reason they suggest blood thinners during pregnancy - and also why you need to take higher than average doses of folic acid. However, my homocysteine levels are totally normal. Therefore, it means that I'm maybe a carrier for the genetic defect, but it doesn't actually impact my health (seemingly.) So my doctors have taken me off the high folic acid. They suggest I take baby aspirin when/if I get pregnant again and that I take the pre-natal level of folic acid. It may be a good idea to get the test on the homocysteine levels to see whether you need to take Lovenox - just a suggestion. Sam.
Did they check your homocysteine levels? It is my understanding that as long as your homocysteine levels are within normal levels, you are not affected by the MTHFR. Mine were but on the high side of normal so I am taking the Folbic as a precaution anyway.
The three I have talked to definitely did not suggest any kind of injections as, in their experience, the extra folic and baby aspirin works while the risks of having too thin blood (injections) are not worth it. I'm sure you've heard that 40% of the population has some form of MTHFR so obviously plenty of pregnancies go perfectly even with the mutation (nice to know and take the precautions though!). One doc also said he has never seen MTHFR lead to a stillbirth, only early miscarriages. That didn't make me feel any better about the future but it means this did not cause my 27 week stillbirth.
I agree it depends on what kind of MTHFR you have, whether your homocysteine levels are high, and how the Protein S factors in (I don't have that). I think you need to ask your doc more specific questions, get a second opinion, or switch doctors until you get one who can be really specific with you and convince you to trust them. At some point you either give over to trusting your doc or you need to get a new one. That's how I feel.
Also, don't trust everything you read on the internet! It will drive you crazy because it is so conflicting! Do some "real" research or call experts until you get "real" answers. There will always be someone out there doing more or less than you...making you second guess yourself...that's why a doc you trust is essential. Good luck!
I will just have to pray everyday that this little one arrives healthy and screaming.