Hi Jojoma:
1) Although the majority of cases of PD appear to be sporadic, there is increasing evidence that genetic factors play a role in the pathogenesis of PD
2)This is particularly true when the age at symptom onset is younger than 50 years
3) A genetic contribution to the etiology of PD is suggested by the observation that approximately 20 to 25 percent of patients with sporadic PD have at least one first-degree relative with PD.
4) Furthermore, a large case-control study found that first-degree relatives of patients with PD were 2.3 times as likely to develop PD.
5) Interestingly in a study on the World War II Veteran Twin Registry they identified 193 twins with PD and concluded that genetic factors were important when the disease began before (BUT NOT AFTER) age 50
6) There are some Familial types of PD associated with identified genetic abnormalities (these are less common) but I imagine as we know more those "sporadic" PD cases may also be associated with a known genetic abnormality...
Dr O.

My 87 ys old mom has it, I
do and my 2 half sisters have symptoms ...we are 87,61,57,53
We all have different dads.

DrOrannge,

Hello and I hope you had a rejuvenating vacaation in New Mexico or Mexico...You are really an example of what a medical doctor ought be. It'sis refreshing to hear honest,straight forward answers to other peoples medical questions.
I have a question:
Is 1 tablet of Sinemet CR 25/100 equivalent to 1/2 tab of Sinemet CR 50/200mg?

I believe their is a genetic link to Parkinson's, since my identical twin brother had it undiagnosed or misdiagnosed for some 20 years (Early Adult Onset Parkinson's Disease). He experienced symptoms much earlier than me. It has been 11 yrs. since my original dx...i am scheduled for Deep Brain Surgery at M.U.S.C. in Charleston, SC for May 12-15. I suggest you just ask others (doctors, neurologists, family, close friends, anyone who sees you on a regular basis and is familiar with the symptoms of Parkinson's).

jojoma,
My name is WJGonza.
You're mother, I suspect, may be the genetic carrier of a defective genetic DNA, since study after study, shows a slightly higher incidence of Parkinson's in female.
May I ask, where did you all grow up? What common factors besides family ties have you with your half sisters and half brothers. Are there many people, in your area, with Parkinson's?

My neuro told me that mine might be genetically inherited, as i possibly got it around the age of 43... He said that i could have a genetic test for it, which would cost atround $600.00.

I decided to not do that, i was concerned that my sister might get it also.

I asked about my children, if they would get it, my neuro said no, as it was my parents who possibly gave me a genetic pd.

And i wont pass it on apparantely

Bumping this for a question I just got
Dr O.