This drug was covered in the PD Foundations webinar this week and that talk should be available on line. Hope it helps you with your stiffness!

Thanks, I always worry a little bit when I have to change or add medications. Will probably wait till tomarrow or the next day to start taking it. I like to read up on new meds before taking them first to see the best way of taking them and what side effects to watch out for too.
Thanks again and will keep posting on how it turns out.

Started the Entacapone today and it's helping with the stiffness especially in my arms. Just makes my urine real dark & bright yellow. Will probably wait a few days or a week before adding the Sinemet ER so if I have problems I'll know which new med is causing it.

Thank you for sharing Slash, I was just given a prescription by my doctor for Entacapone as well to be taken with the Sinemet. I should be getting mine any day from the mail away pharmacy. Does it extend the sinemet? My dr. said that I would be able to get 4 hours out of a sinemet pill. What do you think? I take a 2mg patch and that helps with the stiffness but my Dr. seems to think that if I take the Comtan that I will be able to stop taking so much sinemet. Hopefully, it works. Will let you know.

Not sure if it extends it, but it makes the Sinemet work better. I usually take my doses about 5 hrs apart. I'm on Sinemet 25/100 3 pills 3x a day, Entacapone 200 1 pill 3x a day with the sinemet, then next week add Sinemet ER 50/200 before bed. The Entacapone really helps my stiffness and seems to give me some energy too.

I started entacapone and it did work a little bit better. It was when my neurologist ordered a azilect my symptoms of freezing and rigidity almost vanished. It's a heavy price to pay as now I am on meds every three hours. I have returned back to work since starting these new meds after being off for four months. I have been back to work for two months now and my meds are working great. Yes, there are side effects such as dyskinesias and fatigue which also impact my life. There's always a price to pay when you add more meds.

I wish you all success in your journey. Everyone is different so what works for me may not work for you. Each day that I can be near "normal" I am grateful for. Prior to these meds I was a mess!!

RE- Entacapone.

BREAKING AWAY FROM MY USUAL MODE OF
AVOIDING COMMENTING ON OTHER PEOPLE'S DRUGS,
REASONS BEING, I'M NOT QUALIFIED AND, THE DRUGS SOMETIMES, DIFFER IN NAME, BETWEEN OUR
RESPECTED COUNTRIES, USA AND AUSTRALIA.

THIS WOULD BE LIKE WALKING ON THIN ICE.
DANGEROUS GROUND INDEED.

IN HELPING TO AVOID CONFUSION AND,
WITH MY AIM BEING TO TO CLARIFY A FEW ISSUES,
I FEEL I CAN TALK ABOUT MY OWN, PRESCRIBED MEDICATIONS. COMTAN / ENTACAPONE.

Entacapone,
ALSO KNOWN IN AUSTRALIA AS, 'COMTAN'.

I HAVE BEEN TAKING THIS PRESCRIBED MEDICATION
FOR ABOUT 8 - 9 YEARS.
I CURRENTLY TAKE, AS INSTRUCTED, BY THOSE BEST QUALIFIED, NAMELY MY TREATING SPECIALIST, EIGHT COMTAN TABLETS PER DAY.
THIS BEING THE MAXIMUM ALLOWED DAILY DOSAGE.

I TAKE IT WITH EACH DOSE OF.
DOPERMINE REPLACEMENT, IN MY CASE, MADOPAR,
EVERY THREE HOURS.

COMTAN / ENTACAPONE,

THIS DRUG IS ALSO PRESENT IN STALEVO.
TAKEN ON IT'S OWN,
THIS MEDICATION WOULD BE USELESS.

COMTAN BLOCKS THE ENZIMES, IN THE GUT,
THAT WOULD NORMALLY BREAKDOWN,
THE DOPERMINE REPLACEMENT,
IN MY CASE, MADOPAR, TO DISPOSE OF IT
ACCORDINGLY, 'BEFORE', IT CAN GET INTO THE
BLOODSTREAM AND, THUS INTO BRAIN.

SO BY TAKING COMTAN / ENTACAONE,
THIS FACILITATES MORE DOPERMINE REPLACEMENT
TO BE AVAILABLE. THUS REDUCING THE POSSIBILITY
OF, DYSKINESIA LIKE' SYMPTOMS FROM DEVELOPING.

WHICH MIGHT/COULD/WOULD BE THE CASE IF,
DOPERMINE REPLACEMENTS WERE INCREASED,
TO TREAT, THE ALL TOO MANY SYMPTOMS,
OF THIS CONFOUNDED IMPOSTOR,
WE CALL PARKINSON'S CONDITION.

COMTAN / ENTACAPONE IS AN EXPENSIVE DRUG,
SO TOO IS STALEVO.

AMONG THE INITIAL SIDE EFFECTS EXPERIENCED
WHEN COMMENCING THE TAKING OF THIS DRUG,
IS THE PERMANENT, HARMLESS CHANGE OF
COLOURS OF THE URINE. THESE RANGE FROM
BRIGHT ORANGE, TO A DEEP RED.
NEITHER OF WHICH,
ONE NEEDS TO WORRY ABOUT. LOL

SO THERE YOU GO, AND HERE I GO. LOL

HOW DO I KNOW ALL THIS?
I'VE BEEN THERE, SEEN IT AND DONE IT,
AND I'M STILL HERE.

-------------------------------------------------------
IN THANKING YOU, FOR ALLOWING ME TO SHARE,
WITH YOUR MOST VERY GOOD SELVES,
MY EXPERIENCE WITH COMTAN / ENTACAPONE.

I AM WISHING YOU WELL,
ALL MY PEERS WHO, ARE NEW TO,
AND/OR THOSE ABOUT TO COMMENCE,
THE TAKING OF COMTAN / ENTACAPONE.

MAINTAIN A WINNING POSITION.


" HEY PARKS, UP YOURS, YOU SLIMY BASTARD,
I'M STILL HERE, STILL HERE, STILL HERE STILL,
'I HAVE NOT GIVEN IN".

Stewart / ALIVEO

>>

Slashman, You might try keeping a journal of the medication timing ,dose, ontime, off time, effectiveness, side effects. This will give you and your prescibing Neurodoc a good tool for understanding and adjusting meds. Good luck and good health Alex

Thanks for all the replies. Will think about keeping a journal of some kind to keep track of my medications, side effects, etc. Thought I saw an Ipad app for this. So far my Movement Disorder Specialist seems to be right on my medications and how I'm doing. Know we all have varying symptoms and how some medications work differently for each one of us.