Have you tried witch hazel? It does kill some bacteria and is a mild astringent. It's cheap and feels good, worth a try. I almost always use it nightly to clean my face before going to bed since washing my face is tiring. Hold a cotton ball dampened with it against any particularly nasty acne for 15 min or so, it takes the anger out and can clear it within a couple of days. I don't have experience with prednisone long term so I can't say that it will help, but it certainly won't hurt.

And honestly, one tiny little thing that seems like we shouldn't complain about... sometimes a tiny thing on top of a big thing like MG really is a lot bigger because you're already overloaded. It's only one tiny little piece of straw that breaks the camel's back, remember.

According to livestrong.com website:

Acne is one of the many side effects from steroids. Acne occurs from the usage of steroids because the sebaceous glands on the skin secrete more oils due to the increase of androgen levels in the body from the steroids. Acne of steroid users is most commonly found on the back, shoulders and face. Working out also causes the body to sweat more and increase the oil levels on the skin. Acne from steroids is no different from naturally-occurring acne. However, the acne may be more severe in the case of steroid users.

Read more: http://www.livestrong.com/article/260115-how-to-clear-up-acne-from-steroids/#ixzz2PSf7XBTr

Life certainly is odd. Prednisone has caused me to have some acne on my face. My wife gave me a solution involving vinegar which helps quite a bit. But one shouldn't have to be using Rogain and Clearasil at the same time of life!

Methotrextrate also causes acne in some people unfortunately for me I am one of those but its 3 months off methotrextrate and acne gone thank goodness. Speak to your neuro so that you can be referred to a dermatologist . I was prescribed a topical acne cream called differin 0.1% it really helps.
I use witch hazel and rose water to

Russ, thanks for posting that! I've been asking all my doctors whether the steroids are the reason that my hair is falling out and I don't get my period; they say no. But then I was thinking, I know steroids cause acne in some people (they don't for me, incidentally) and I was wondering if it was related, and caused by hormone levels being disrupted.

And, I agree with MayMayKnits, sometimes the little things are the hardest to deal with on top of everything else.

In addition to making my face HUGE and break out, I had issues with my hair falling out too.
Now that I am on lower doses of prednisone, my hair has grown back and my skin has cleared up.

I used (use ;) ) neutrogena soap. It can be found at the grocery store or drug store in the facial product section and only costs about 3 dollars. Lasts me about a month. It "melts" faster when it gets wet so keep it out of the shower stream.

Hope this helps... one less thing!