Myasthenia Gravis Support Group

Myasthenia gravis (MG) is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. The hallmark of myasthenia gravis is muscle weakness that increases during periods of activity and improves after periods of rest. Although myasthenia gravis may affect any voluntary muscle, muscles that control eye and eyelid movement, facial expression, and...

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Is Wellbutrin safe to take when you have MG?

CarlyMichelle
CarlyMichelle
I'm going to ask my neuro about it, but I wondered if any of you had experience with it. This would be used for anxiety more than depression.

Thanks
Carly
deleted_user
deleted_user
Carley a while back I was gonna do the Wellbutrin and my neuro said was ok to take...Mine for anxiety also which I have tons of..I decided not to take for some reason but she did say was ok..I do the klonopin for anxiety but not working anymore but also giving me weird side affects now cause been taking a long time so not sure what to do...But keep me posted on if you take and how it works for you..Good luck...Hugs
GreenMarie
GreenMarie
I know that a lot of people take this medication successfully without problems but I found a site that lists some reports of muscle weakness but these are not specific in these reports to known MG.

http://www.ehealthme.com/ds/wellbutrin/lack+of+strength%2C+muscle+weakness%2C+weakness

It appears that of the people reporting side effects 3.71 reported muscle weakness of varying degrees.

My only experience was decades ago when I did not have muscle weakness. I only took it for a short time, less then two weeks. It caused me to have a witnessed seizure in which I fell to the ground cracking a rib. I did not have a known seizure disorder but it seems to have lowered my seizure threshold.

Not sure any of this is applicable. You will no doubt be starting at a low dose so I think if you are watchful you will be able to judge if you have changes. Also with this sort of medication it is good to have a friend or family member watching you for changes in thoughts, mood or behavior.

I hope you find something that is helpful! Marie
deleted_user
deleted_user
I take Mestinon 180 MG twice a day and I take Wellbutrin 450mg a day taken in the morning. I have been taking both for 3 years and Wellbutrin much longer 10 years or more. I have no side effects with Wellbutrin and with Mestinon only gastro- intestinal side effects which are currently under control thanks to pro-biotics and cutting dairy from my diet. Everyone is different, so check with your doctor and get his opinion for sure. Hope you find what works for you!