I was taking it regularly every 3 hours to avoid the dips.

I agree with logos66, but you Can Take It whenever you Want. I am late sometimes like 1-2 hrs and i Take It every 4 hours. But i would reccomend to Just Take It regularly because from Your description It seems like you could maybe try to avoid afternoon weakness by taking mestinon at morning.

I agree, I do my best to take it every 3-4 hours, even if I feel okay. I tend to get off schedule on the weekends, then realize that I have not taken it as I should.

Maybe that will keep you from feeling so weak in the afternoon, as I know the later in the day is harder on me.
Annette

What you are feeling is normal. MG generally renders us weaker as the day goes on. So, Mestinon taken at 8AM, will not give you the same strength @8PM, but you could adjust(increase) dosage etc(caffeine...) to improve the signal later in the day to get better results. Depends on your day.

You will not do any further harm to yourself by not taking it, you would just be dealing with symptoms perhaps.

Whether or not you take it on a schedule is up to you, but I think that is best when you first start it and until your MG is controlled. Once MG is controlled(by getting treatment(s)), take it whenever you feel like it, if you feel like it.

Peace,

TJ

I tend to be strict with my medication. I recently tried cutting back on my mestinon by skipping a morning dose and it set me back for the entire day. Lately I've actually increased my dosage, not by much. A half tablet will often keep me in check until the next full dose.
Stay well.
Larissa ;)

When I first started I took it about every 5 to 6 hrs. I got much worse. Now I take it with in 5 or 10 min of every 4 hrs. Sometime early some times late but if I am 20 or min. late I get symptoms.
Will

These hot, busy days, I take the 60 mg before I get out of bed, uaually with an early wake up around 5:30 and then take it at 7, 11, 3, 7, 11. The last dose I take at bedtime which is often earlier. I need the regularly scheduled doses to function well all day and sleep flat all night. The 7 am dose I take with breakfast, so that may not be strict, but it is important for me to get about 120 mg in before I get going and may need an occassional boost between doses which can be a chocolate square or half a pill.

I agree with Larissa that, in the beginning, to function best the medication needs to be pretty much around the clock. After immunosuppression really kicks in, that may not be so necessary. b

I'll set my alarm on my phone for my mid day doses, since every four hours works best for me, and if I forget and go five or six, I can really feel it.

I usually feel weak in the morning becuase i only take mestinon waking hours. Does anyone else feel this way?

I've recently started a mestonin trial and am struggling with the effects in the stomach. So i am only taking it once per day.

Myastheniag, You are probably weak in the morning because you aren't taking anything during the night. Some people take a time span before bed which lasts the through the night. Others set an alarm in order to take it in the middle of the night, so they don't wake up weak. I will mention that time span doesn't agree with everyone and I am one of those people.

Restorativepose, Are you taking Mestinon on a empty stomach? If you need to eat something prior to taking Mestinon it should help with the stomach upset.

After trying various doses over different time spans I've found that it's best for me to take a 60mg tablet 5 times per day but shorter gaps between the last 2 doses at night. I have them at 8am, noon, 4pm then 7pm and 10pm, sometimes I have an extra half tablet later at night or if symptoms are really bad. I'm usually ok during sleep and when I wake up. One thing I have found for me is (maybe at the weekend when I try to get a lie in) I will still use the alarm to wake me for my 8am tablet, go back to sleep for an hour maybe and then wake up with eyes that dont want to stay still, my sight isnt blurry, no double vision but they wont stay in the position I want them in which makes me kinda spacey and of balance. So maybe I should just take the tablet when I naturally wake up or just not lie in ( I know which one I'll go for!!)
Basically I stick to the set times for my tablets else I really suffer later in the day.
Kim x

I take 60Mg in the morning then 90 Mg every 3 hours there after. I was good with taking it with little or no food until the dosage got higher. Now I have to eat every time to avoid bad stomach cramps.

Kimber

I take 90mg starting 6am every morning, then at 10am, 2pm, 6pm and a timespan around 9 or 10pm. If I have symptoms I will add an extra 30mg or take closer together at 3-3 1/2hrs. If I try to decrease my dose I generally pay for it later. I am looking forward to the day I can scale it back and not have symptoms.

Can I ask if anyone has ever been prescribed a med called Nuvigil. It is a controled substance. I took it for two weeks, but it just made me jittery, I was still weak.

Sometimes I feel like I could OD on caffine. I am not even supposed to take it. (it is literally against my religion!) But it also just works on part of what is weak. I can't even describe it.

Does anyone relate to that one. How does Mestinon feel different. My PCP looked at me like I was asking for Crack!! He said, I don't know the first thing about that stuff. It isn't just him.

Is it a dangerous med. I think I would rather take a medicine that could make me very sick to my stomach than to have a spinal tap. I think others would be with me on that.

It's like they don't want to be responsible for MG. I think doctors are for the most part very afraid of this disease. They want to pass you on to the next Dr. It would almost be funny if it wasn't so aggrivating.