I am on tinzadine (zantaflex)and it works BUT it makes you very sleepy. I only take it at bedtime. At least it does for me. It works better than Ambien. Happy dreams!

tinzadine is a muscle relaxer. I hope it helps.

"I am on tinzadine (zantaflex)and it works BUT it makes you very sleepy. I only take it at bedtime. At least it does for me." That is worth repeating. Very few things can knock me out, but tinzadine is one of them. I will notg take it until I know I can be in bed in 15 minutes.

Yes, tinzadine does wonders for spaticity at night for me. It lasts about 4 hours.

I also take it at bedtime. It does work for me too. And yes it will make you very sleepy. I would not take it unless you are going straight to bed.

In total agreement with others. I take Zanaflex and Neurontin. I can only take my Zanafkex at night too...as it knocks me right out!

I ran out of my Zanaflex about a week ago...& have been having serious issues with my spasticity! Have tried ALL the others and I go back to my Zanaflex everytime. It's the best I've found for spasticity & the muscle spasms. Hope you have good luck with it too. ;)

OK, the follow-up question is, how much do you take a day? He only is prescribing 2 mg at night for a couple of weeks, and then add a pill in the mornings for a total of 4 mg/day. Now I am slightly nervous of taking a morning dose after what most of you said about sleepiness (although with my ultra-stiffness, maybe that won't be an issue?)

He gave me the impression that he only was giving it to me because it is the protocol, to first try Baclofen and one other muscle-relaxant before resorting to Sativex (the newish cannabis-based one) which it is pricey (and the state would pay for!?) tjquiver- are you mostly happy with it 'cause it helps you sleep then?

Mine is 4 mg at night.

Mine are 4mg. I've tried the 2mg...& I can tolerate those during the daytime.

Just to follow up. . .I am now taking the full 4 mg per day, but due all of your feedback (which I agree with completely, that it lasts about 4 hours and makes me sleepy) most of the time I take only half of one at bedtime, the other half when I wake up mid-way through the night, and then in the day I do a couple of half pill doses.
I have got it into my head that it is better to slowly dose myself during the day rather that taking the full pill a couple of times. I have no idea if it just a silly idea of mine, but I have been doing it with the baclofen for awhile now.
Thank you all for telling me about your experiences!

I have been taking 2 mgs at night for years. I need more because sometimes I have to take an extra one and u run early so that makes it rough.

I also take Tizanadine 4x day 4mg. I was taking it with 20mg baclofan 4x a day. And originally I was tired. I just had the Baclofan pump inserted and have found I am not as sleepy. It didn't wipe me out completely. Just sleepy.

I also take Zanaflex. For some odd reason it doesn't make me sleepy.
Chrissy

I was d.s. 4 years ago with m.s. was on copaxine 1 year didnt help my spinning,my eyes are my biggest problem,been on tysabri 15 infusions once a month for 15 months hasnt helped my eyes but they think its holding everythink else at bay,I take 4mg tizanidine at night has controlled my spasms in legs and I was lucky enough to buy a massage chair which has done wonders for my muscles and relaxes me,tizanidine is the only med that didnt make me totally dizzy,and it dosnt make me tired everyones system is so differant,write back would love to hear from you katti.

Zanflex - 6 mg at bed, then another 2 mg. in middle of night when I wake up to use the bathroom and can go back to sleep. Baclofen - I use that during day and at bedtime - 10 mg. 4-5 times a day.