I'm on both of them and I still have the extreem pain and spazems galore!
Exersize regularly is suppose to help. I did physical theropy several times. You have to keep a pattern and don't finish.

Hi! I have been on both before. Amitrypilene made me gain weight, which is I understand is common, but it worked pretty well. Cymbalta was one of my all time favorites. I was almost completely pain free, but after about 3 weeks I started getting headaches and migraines. But I get them quite frequently and I have lots of triggers for migraines. But if you don't have this problem, I would definitely give it a try. I was really disappointed when I had to discontinue Cymbalta.

Hey carolinagirl!!! I am sorry that you are having so much trouble with the pain in your legs! I am sure the hot weather is not making it any better. I think that trying Cymbalta could be a good thing. It is advertised as helping with pain...worth trying!

I too suffer from the hips down to my toes. At one point all I could do was cry from the different pains zinging all over my lower body with no warning where to hit next. My neurologist did his thing with steroid iv's and neurontin. He finally told me to see a Pain Management Specialist. I neve heard of that kind of doctor, but I understand they are coming into the field of medicine as a highly respected one. Anyway, I won't bore you, but I've been on Ultram, Lyrica, Cymbalta, and maybe some others I can't think of right now. I am still working with the PMS to find the right "cocktail." Everyone is different and can tolerate or not different levels of pain. I would like to encourage you to seek this counsel if at all possible for you. I know that I am smiling these days and walking farther than back and forth from my bed to the toilet! I'm not 100% there yet, but I now have faith I will be soon because of what my PMS has done for me. I'm sorry you are dealing with this, and I understand your pain. I wish you the best of luck and don't discount this route. You may too be surprised at the change in your life! Lynne

I went to a pain management doctor for about 2 months. They gave me percocet at first, it did not help my pain at all. Then they put me on loritab, it didn nothing. I quit going because i didn't find any relief and just went back to ultram taking higer doses. Its seems to work better than anythin ive taken, I take about 300-500mg. a day. I worry about what it will do to my body long term taking this much medicine. But it seems if im having nerve pain that neurotin or lyrica would help but it doesnt. I give up.

I take gabapentin, a generic form of neurontin. It is my understanding that some people take as much as 1600 mg/day, while I am doing well on 400 mg/day. If I don't take it, I am miserable for two days until it is back in my system again. If I take it regularly, I am pretty much pain free. I wish you the best of luck!

I was prescribed Lyrica for leg pain and it seemed to work somewhat.

Good luck!