First I want to say that I have no diagnosis yet, after 20 plus years still clueless. My New PCP since I moved to Texas was the first physician that said lets do an ANA test. I've done 3 in the past 4 months and they all came back positive. However recently my pattern changed from Speckled to Homogeneous. Well a little about my symptoms: headaches, lower back pain on the right, chest pain on the left side, fatigue, shortness of breathe, muscle weakness including falling and tripping over things often, dry eyes, constipation, increase in bladder, numbness and tingling in hands and feet, feeling of cold water running down my legs, electrical shocks going through my back and legs, hand tremors, muscle twitches that has resulted in my arms jerking out and tossing things out my hand, confusion at time, GERD, etc. I've been to two Neurologists and two Rheumatologist. The only test I've had was repeat of my ANA which was positive all 3 times, nerve test and muscle test in my arms which was normal, EEG which was normal, EKG which was normal. My neurologist is pushing for me to do a study for about 4 days in the hospital to check for seizures activities. It seems like that's all he's focused on. I did have an MRI almost 2 years ago that showed some hyperactivities but my current Neurologist want to check for seizures before doing a follow up on the MRI or other test. So I'm thinking about getting Neurologist and Rheumatologist number 3, or is the sleep study the right test I should be taking?