I have been taking Imitrex for several years. This year is the first time they have allowed generic versions of Imitrex. I take the injectables. I was very worried but I personally found no difference in the drugs. I can tell you that I have had many times when I needed 2 doses and then went months when just one worked. Every person is different. I hope and pray you feel better.

If you can try not to to take Imitrex more than 3 times a week cause it can cause rebound headaches-whech are worse headaches from having taken too much medication.
I take Imitex too, but try not to to take it that often and definately not nore than two times in one day. Try an ince pack, heating pad, Excedrin Migraine or another Triptan if you can.
I'm struggling w/Migraines myself.
Also, Look at a "Migraine Diet" that really helped me! Some foods were giving me terrible headaches!
Good Luck!
Ecca

I almost always need the second dose. Definitely take the first dose the moment you feel the migraine coming on . Do not wait for it to become full blown. Since you are on Medicaid, I'd ask your doctor's office for some samples. I prefer Maxalt, but my copay is $80 per month. My doctor loads me up on free samples. You should also ask for a backup med if the triptan meds aren't working. Toradol is an option, but your doctor might have other opinions about a better second line med.

I have had similar experiences with the generic imitrex. My headaches often come back over and over again for 2-3 days (sometimes longer). Some generics are better than others. My pharmacy was willing to order in one that I liked better even after they discontinued use of it.

Also, my doctor at the diamond headache clinic has prescribed me dexamethasone for when the headache keeps coming back or won't go away. It breaks up the "cycle" and you avoid overusing triptans.However, it is a steroid and is not recommended for prolonged use. It does seem to work though.

You might ask your doctor about non-triptan abortive medicines for when the imitrex doesn't do it's job. There are several different types- Keterolac, soma (muscle relaxant), etc. Good luck!

I found that Imetrex injections, over time, gave me panic attacks, a great addition to a Migraine. I have had much better luck with Axert. Also, I have learned to take the medicine as soon as I think i need it, don't wait until the headache is roaring out of control.
Good Luck

my experience with generic imitrex has been good. except our old insurance, aetna, covered 18 per month and the new insurance, united covers 4 with refills every 10 days. a real nuisance. i've got no advice to you other than try a different medication.