I've been using Prednisone to minimize my symptoms and increase my energy. I don't take Prednisone much, but a short course helps me to have an enjoyable trip. Also, airlines have wheelchairs and people who are happy to wheel you about. You give them a tip. It takes a lot of wear and tear out of going through airports. If it's a sunny place, I am careful with sunscreen. I also get a lot of rest, usually crawling into bed earlier than anyone else. Then of course when I get home, I crash and I usually have some days set aside for me to have a "vacation from my vacation." Have fun, but be careful. A sunburn can set you back.

Hello. I have travelled a lot with lupus. First thing I would say is that if you are going out of country make sure you have some kind of travellers medical insurance in case you need medical care while you are away. I always thought it was a waste of money until I was in Cuba once and had to go to the hospital with a flare. Secondly, do not push yourself. Especially if you are changing time zones or travelling at late/early times make sure that you get enough sleep. It may seem like you are sleeping away one of your vacation days but it is worth it. I traveled to Vegas a few years ago and got in very late but made myself get up the next day early so I wouldn't waste a day in bed. I ended up triggering a massive flare and spending the rest of my trip in a wheelchair. Speaking of wheelchairs, most hotels and airports have them that you can borrow (sometimes for a fee or a deposit) and if you are like me and can trigger a flare with a lot of walking don't be afraid to take advantage of them. Other than that, as its already been said, if you are going somewhere sunny, stay in the shade or wear LOTS of sunscreen or protective clothes.
Really, I think its about listening to your body, not pushing yourself to hard, not feeling guilty about taking time out to rest, making sure you have all your meds I travel with prednisone even though I don't normally take it, in case I have a flare), avoiding triggers like sunlight and then just relaxing and enjoying your trip.
Hope this helps. Enjoy your travels.

Good advice so far.

HYDRATE before, on the plane, and after the plane. They'll usually bring you water if you ask.

If you're going to do steroids - ask your doctor for a z-pack to take with you just in case - most will oblige.

WASH YOUR HANDS ALOT.

Don't drink any water that doesn't come from a bottle that's SEALED if you're travelling out of country.

MAKE SURE you have enough meds for the ENTIRE trip plus a few days.

Take frequent rests whether you think you need it or not - by the time you need it...it's too late.

Just relax and don't stress. Make sure you have the meds that you need for traveling. I have went to Jamaica twice, Detroit twice, Delaware beach once, Georgia four times and other places and I have done well. Make sure you drink plenty of water. Try not to be in the sun for to long but enjoy yourself. Get plenty of rest.