Insomnia Support Group

Insomnia is a symptom, rather than a disease, and is characterized by inadequate quantity or quality of sleep. People with insomnia complain of difficulty falling or staying asleep, which results in significant impairment of daytime functioning. Insomnia is categorized as transient (shorter than one week), short-term (one to three weeks) or chronic (longer than three...

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Does Seroquel stop working?

deleted_user
deleted_user
My psych had put me on 200 mg of Seroquel which helped me sleep tremendously. Over time, the dose has had to go up, I went up to 300 mg, took myself up to 400 mg. Now 600 mg doesn't seem to do anything. I don't know what to do. Has anyone else found that to be true and had the same issues and what did you do? I can't sleep at all without it but I'm barely sleeping at all. I've had very severe insomnia that regular meds don't touch.
deleted_user
deleted_user
I used to take that for insomnia. However, if you go higher in dosage like you did it may not be effective for insomnia at that dosage. Usually for insomnia people don't take more than 200 mg. In fact, for insomnia the range is usually between 25 - 100 mg.

One thing that I found was after a period of time, it stopped working even at the lower dose so I would cycle off and then go back on. Good luck.
bruticus
bruticus
your brain will definitely get used to anything. take for example.... salt.

If you use salt a lot, then you need more and more salt to get the same effect on your food. If you just stop using so much salt, eventually, you don't need so much to get the same effect.
bradkling
bradkling
I too was helped by seroquel for sleep...I’ve been on 450mg for almost eights years and does not knock me out anymore. Our bodies grow tolerant to the med and then we try to up the dose only to find it doesn’t work either. Seroquel has a strong antihistamine effect but according to my doctor my antihistamine receptors are maxed out. He wants me to stay on the mend for it’s other helpful properties.
BrainDeadPineapple
BrainDeadPineapple
I have to cycle on and off different medications. I’ll get to the highest dose and once it stops working...back to the one I was on before. Hopefully you have a good doctor that doesn’t need to see you every time your medication stops working and you need to change back to another!