Hemochromatosis Support Group

Hemochromatosis is a hereditary disease characterized by improper processing by the body of dietary iron which causes iron to accumulate in a number of body tissues, eventually causing organ dysfunction. It is the main iron overload disorder. Hemochromatosis is notorious for having symptoms that are often initially misattributed to other diseases.

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Megan-Leigh-McDonald 05/03/2011

I have run into a mention of this amino acid a few times in researching HH and wondered what you guys know about that?

I don't really understand if it's a deficiency or the opposite or if it's just switched places on the gene?

I didn't do that well in science either - mostly because of the math and probability involved in genetics LOL.

Any help would be appreciated.

thanks
Meg

YREKADC 05/03/2011

GAZOONTITE MEGAN... JUST KIDDIN.. I HAVEN'T HEARD OF THIS, OR JUST DON'T REMEMBER. I SHALL LOOK INTO IT. I WAS GOOD IN SCIENCE BUT AWFUL IN MATH... GOOD QUESTION THOUGH.... TAKE CARE NOW. DC

Megan-Leigh-McDonald 05/03/2011

YREKADC 05/09/2011

OK MEGAN I LOOKED INTO IT AND I HAVEN'T THE FOGGIEST IDEA WHAT THAT SAID???? BY SCIENCE I THOUGHT YOU WERE TALKING LIKE COMIC BOOKS SCIENCE. I WAS REAL GOOD IN THAT CLASS.
REALLY THAT IS HEAVY STUFF. I HAVE BEEN READING SO MUCH ON HH AND KIDNEY STONES AS OF LATE, I THINK I AM OVERLOADED WITH DIFF INFO...... YIKES!!
SEEMS MOST THE THINGS I EAT WITH OXALATES IN THEM, NUTS, POTATOES, ETC CAUSE KIDNEY STONES, THAT I HAVE BEEN PLAGUED WITH FOR ALMOST A YEAR...
ANYWHO I HOPE SOMEONE ELSE CAN BE OF MORE HELP.
OH WAIT A MINUTE IT HAS SOMETHING TO DO WITH ANTIOXIDANTS. THOSE I KNOW ARE A GOOD THING.
SOME TYPES OF ANTI OXIDANTS HAVE ALLOT OF IRON IN THEM. IE CHERRIES, GREAT FOR ANTIOXIDANTS BUT TOTALLY LOADED WITH IRON....
PERHAPS IT HAS BEEN MENTIONED AS AN ALTERNATIVE SOURCE OF ANTIOXIDANTS??
OH DARN NOW I HAVE TO GO AND LEARN MORE NEW STUFF!! JUST HOW MUCH LEARNIN DO YOU THINK AN OLD MONKEY CAN STAND???? WELL ANYWHO I'LL LEAVE IT AT THAT. HAVE
HAPPY PHLEBBINGS AND TAKE CARE. DC

deleted_user 05/19/2011

Histidine has to do with the actual section of the defected gene. The original gene (histidine) is replaced in the H63D genotype with apartic acid:
histidine-to-aspartic-acid substitution (H63D)
for more:
http://www.ncbi.nlm.nih.gov/pubmed/10073265

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