I take 100mg also. I still get break through depression ( I call it that). I am thinking of asking about a different med also. Good luck to you. ~ Suzi

I was on Zoloft for about 2 years. It helped me for a while and had little to no side effects. About 4 months ago my doc switched me over to Effexor. I love it. I have NO side effects what so ever and I can see a big difference in how often I have mood swings, break downs etc. It is normal as a human to have emotions, and when I was on Zoloft, I had none. I couldnt cry or anything. My friends and boyfriend used to tell me that I was emotionally retarded. But now on the Effexor I feel like my self. Thank you whomever invented the "happy pill" I bow down!

Zoloft and I didn't get along...Effexor is my new friend.
Cindy.

Iwas increased from 50 to 100 and now to150.It seems to be helping,but I need more time to tell for sure.

Zoloft 50mg works for me most of the time and I prefer to take the least amount possible.(I liked kaydak7's comment about "break through depression"--sometimes no amount would be enough) and there is the added benefit of Zoloft's side effect of loosening the bowels--great to combat constipation of FM!:) Gotta love it!

Hi, I have never taken Zoloft but just had to switch from Cymbalta back to Effexor. Cymbalta just stopped working and I had a full blown depression on it. I felt the depression lift once I got back on Effexor and I am very happy about that. Hugs, Keleee :)

Interesting reading the posts, because those were my experiences. I felt numb like I couldn't cry for nothing. Also, I had to go to 150 mg. and I just felt "numb." I switched to Prozac, which is "Fluoxetine" generic, and I take 60 mg which is 3 tabs. I find that it's the best for me anyways. I have tried several others too. You have to find the right one for you. I think you should try something else. You may be one that the Cymbalta will help the fibro too. So, try something else. I think it's a good idea. I feel so much more normal on Fluoxetine.

i don't give advice. i take zolfo 200 mg. but also take wellbriten 3 x times a daywhich is 150 each. it has been helpfull with both since 1992

I was on zoloft 120mg for a bout a year and was total zombie, i had it for depression and anziety, i ended up with a completely retarted digestive system, which aparently is becoming a major issue for particularly women. I'm on maximum dose of lyrican and it cushions the crashes but increases fog. Cymbalta i hear for those who can take its a wonder pill, but those who can end up feeling like thier loosing it or on speed. I hope somthing does the trick !

Hi. I tried zoloft and hated it...I tried Effexor and found it helped for a while but the depression came back and it did not help with my panic attacks. NowI am on Celexa (60 mg) and Welbutrin XL (300mg) together they have helped me feel like I have my life back!! The panic attacks are almost completley gone andthe depression has lifted. I se ethe world in a completely different light now and know that I am a much happier person. Every drug works different on everyone. Talk to your doctro if you do not feel like your med is not working. Trial and error may be a big apin..but so worht it once you find the right med or combination that actually works for you! Good luck
Donna xoox

Sorry everyone . My typing is almost unreadable today. My fingers seem to have a life of their own today! Have you any idea how long it has taken me to type this without mistakes!! lol

I was just increased to 150 mg once a day.Too soon to tell for sure,but I think it did the trick for me,Kev

My experience with Zoloft was horrible. I had been on other types of antidepressants in the past and since. My experience with Zoloft was like nothing else. I was worse taking it than off of it. I was crying every day hysterically and was severely depressed and suicidal, and I wasn't that bad before the drug. I had to be hospitalized and the doctor at the hospital said that I shouldn't have been taking it (that it was the drug). that dr. stated that even if i myself was not bipolar, I had family members who were and zoloft is very bad for people with bipolar or those with similar genetics. i never knew that. This drug really freaked me out. Maybe ask your psychiatrist about this especailly if you or a family member are bipolar. A different drug might be better.

I take 100mg of Zoloft a day. I went off it because, I thought it was making me sweat. They put me on Prozac and it made me want to put my head through a wall. Then they put me on Depakote and I couldn't see to walk, It was like I wasn't in my own body. Now I'm back on zoloft and I take trazadone. It works for me. I have to take 2 different pills to help me.
My sister takes Prozac and that is the only thing that helps her.
You see, u have to try different things to find what is right for you.

I'm on 200mg of zoloft, and all it does is help to curb hostile feelings. I've been on pretty much every anti-depressant and anti-psychotic and none of them have done much.

At the same time, I know a girl who takes only 50mg of zoloft and it stops her symptoms completely... so you never know. I wish I were that lucky.