I've been taking Savella for a year and a half. Initially I had good results. It took about 4 months to adjust to it and the good results lasted about 6 months. I'm considering making a change but sometimes I feel like I should maybe leave well enough alone. I'm just not very well most of the time. I'm also afraid of having to adjust again to something new. I would say it probably helped my fatique the most. I hope it works for you.

I have been taking this for 2 years now and was skeptical until my rheumy said I could try going off it. When I stopped taking it my neck and shoulder pain were worse and the fatigue was terrible. Now when I try to go off it I am hit with fatigue right off.
I am beginning to think there is nothing that can really help the pain. Problem is that I have RA with Fibro and Lupus and it is hard to know what is causing the most pain at any given time.

Thank you for your replies. My insurance finally accepted Savella and I just got it filled today so I start it tonight. I pray that it helps because so far. nothing else has! This is just so frustrating....I just want the pain to be at a more tolerable level.

Did it help?

I have been prescribed Lyrica. Have had immediate weight gain and swelling of feet and hands. I also take Cymbalta in the AM. I am going to ask my doctor if I can change to Savella. I just recently got off diabetic meds and don't want to get back on them. I was down 12 pound, but now...gained it all back. I am pretty sure my diet has not changed that much. So depressing. I had gone from 100 mg 3 times a day, to 75 mgs 3 times a day and I am now on 50 mgs 3 times a day. Pain relief is very noticeable if I miss a dose as I have tried that as well.

I heard Savelle is very very expensive