Just out of curosity - did you titrate on that medicine - build up slowly? Also, did you try taking doses in the middle of a meal (so that additional food followed it)? I haven't tried Savella yet (I'm deciding between Savella and Cymbalta) but, I experience nausea constantly because I take multiple medications with that side effect. I am never without Saltines and tea (unsweetened). Drinking plain water makes me more nauseated. Did anything give you substantial relief?

2puppies has a point. Food before and after Savella will help. I take 50mg. 2x a day. I was on cymbalta didn't do a thing. lyrica was a no go and neither was gabapentin(neurontin). I also take Topamax with it for the migraines. I'd have to look at the bottle to check the dose. I can't always recall that one. I believe its 50mg 2x. The Darvacet 600mg for flare ups really comes in handy and the methacarbamol for the muscle spasms 600mg 4x.

I do take it with food or else I would throw up. I just started 4 days ago on 25mg per day in the morning. It's making me a little sick and very tired. I go to sleep early now and can't sleep. I also take ambien cr to sleep. If I didn't take that I doubt I would sleep during the night. I was on cymbalta for 3 months and I had the WORST side effects. I decided to go off and it was the worst drug to come off of. When I went off Savella before it was nothing like Cymbalta, I have pretty serious headaches too but I am suppose to go to a neurologist. They will most likely tell me I am fine like all the other doctors. I will keep you posted.

Believe it or not I take 150 mg. a day. I think it helps along with everything else that I take. I truly have not had nausea but I have lost a lot of weight.
It also does make you a bit restless and can cause sleeplessness.
I don't know--everyone reacts differently to different meds. I think it helps, but if it doesn't help you maybe it's worth it to come off and try something else.
Being nauseous all day is not fun.

I started three weeks ago. Eating a little before and after the pill helps most of the time. I am not sure whether it makes sleeping worse as I haven't sleep well in so long that I can not blame it on the Savella. I haven't had another bad flare up since I switched to it. I am not alot better but not worse either. How long before I sould see an improvement? any thought from anyone that has been on this for awhile?

Hi guys,

I actually had to go off it was making me really sick. I am currently on Elavil and so far I feel great. I am hoping I don't get weight gain and have sexual side effects. I will keep you updated.

I titrated up to 50mg 2x per day and I thought I was doing okay, then I had a lil fibro flare and my dr increased to 100mg 2x per day and I started having panic attacks. I've had an elevated bp off and on for months but we weren't sure what the cause was. I went back down to the 50mg 2x per day because of the anxiety attacks, but when I saw my Rheumy last week he said my elevated bp was probably due to the Savella also, and decreased my dosage to 25mg 2x per day.

So I'm pretty sure that Savella not only increased my bp but also made me more depressed and anxious. The thing is, I looked back in my journal and I realized that around the same time I reached the therapeutic dose of Savella (50mg 2x/day) I started getting depressed and anxious. Prior to Savella most of my entries are about physical symptoms, medications, dr appts, etc. After I began taking Savella it's mostly emotional, talking about anxiety and depression. Had anyone else had this problem? Or heard about it?

I take Savella in conjunction with Seroquel to get a decent night's sleep. 100 mg. Savella to fall asleep and 200 mg Seroquel to stay asleep. That is the extent of my sleep disorder. Pretty bad.

I have no side effects from Savella.

Mizroze

Has anyone gained a lot of weight off this med, now that i have read how bad Lyrica is my doctor also talked about this med to me too so now i think i have a decision to make.

I had the same problem!!!! Was sick feeling ALL the time!!! Wasn't worth it for me, so STOPPED all drugs and only take vitamins... I has been almost a year and I feel better then when I was on prescription meds!!!! I will never go back to prescription meds... and I've tried them all for FM... and all they did was leave me broke... the key is inside your self...

Managing stress, sleep and the right regimen of vitamins....
Ones that really helped me are: V-D and acetyl l-caritine (but I also take a multivitamin-kroger brad because they are gluten free, and a zinc, magnesium and calcium pill)

And the sweet thing about only taking vitamins as that you don't even have to go see a doctor, which is awesome because they are all just about as dumb as a box of rocks anyways!!!

Oh, and I stay away from gluten!!! Alot of people I know with FM stay away from gluten and it helps alot as well!!

Best of wishes
Sar

I take Savella and I truly love it. It works miracles and I do notice a huge difference when I don't have it. My doctor has actually made up a great cocktail that until the cold weather set in was doing wonderful. I take Savella, Flexeril, ambien, and I have just started taking Meloxicam. I have only taken 2 days work of the meloxicam but already notice a difference. Like laughman I suffer from severe complex migraines and take Topamax and verapamil for them. We finally have those under control. It looks like she is also prescribing buspar and neurontin on my next visit. So I would certainly recommend using the savella it has worked wonders with me.

I have been using savella but can only take one dose of 50 mg at night and I had to work up to that very slowly. I tried to take it twice a day but I feel too lethargic if I take it in the morning. My overall symptoms have improved but I am getting stomachs pains and acid reflux. Anyone else experiencing any stomach pains?

Whats the highest dose of Savella anyone know that you can take?

I am alena I am new. I have had fibro for about 2 years. I take sevella. Wonderful drug, decreased my trigger points down to half. I do have problems with nausea but I have more problems without it. I just eat alot of plain cheerios and I do well and gatorade. I also take Topamax and sometimes Zofran for nausea, ask your dr it works really well. It takes away the nausea in minutes and I can go about my day which is important for a med student
alena

I just got started on savella and my tummy hurts >.< (non related>)my nerves r goin crazy right now i feel like someone poured anti freeze into my blood or something. i woke up from a tummy ache today i might have to stop taking savella. I cant ever get to sleep or stay asleep. I wake up like 6 times in the middle of night and all the pills i have to take its like impossible to sleep right or do anything for that matter. this is so stressful lol im sick of how bad it hurts, the shaking and loss of breath are really starting to get to me. I'm gona ask my doctor about massage or water therapy, ive been forcing myself to deal with all this pain for several years and its pinning me down into a corner where i cant move =/ i feel like this is completely impossible to deal with without someone close to me and i just dont have that at all either. Fibro + lonelyness is HORRIBLE lol Ive been dealing with this since about jr high school and i honestly just dont know what to do but im pinned down so badly that it looks like im giving up =( they are trying tons of different anti depressants on me but they r all just making me worse... i dont even see any positive side effects from anything besides the gabapentin and ibuprofen