Dixie, Effexor XR is the big guns. It is stand alone antidepressant. I went of Cymbalta and back onto Effexor and felt better in a week once I got up to 300 mgs.

The depression I had was history! It's a good drug but not without side effects.

Good Luck, Kelly :)

I''m not going off cymbalta, it has made my Firbro almost pain free but has done absolutely nothing for the depression and right now I am at the bottom of the bag!!

For some reason my doc took me off the prozac I was on at the same time I went ON Cymbalta. He weaned me off of the prozac and then slowly increased the Cymbalta. I DID have a doc (now retired) who used to give me two antidepressants at a time. She was unusual though because my other docs were always asking why she did this.

I'm only on Cymbalta now, 60 mgs two times a day. I'm really not sure how it's working, but I've been on it for at least 9 months. The first month I felt kinda nauseous for a couple weeks, after that it went away.

Again, I'm not feeling 100 percent as far as the depression goes, and I think I might need something else.

Anyway, I hope you get some helpful comments from others. I'm interested because I feel that I'm in the midst of a pretty serious depression myself....

Thanks for the post.
Morus

I'm on 90mg and it isn't touching the depression but works wonders for the fibro pain.

I am on Cymbalta and Klonipin at the same time. Family Dr. put my on Cymbalta and Psy.Dr. put me on the Klonipin with it. It has helped my depression some what but I think that the doses need to be adjusted. I also take fish oil (per Psy. Dr.) for depression and B12 shots. Hope this helps.

I thought Effexor worked pretty well for me and it seemed to have not that many side effects, aside from weight gain, which you're gonna get from pretty much any antidepressant.

The first time I took Lexapro it worked well, but when I started taking it again along with my Fibro meds, it made me extremely jittery.

Your dr would probably be the best person to ask.