I wonder for how long you have been on your medications?It usually takes about 4 weeks to know for sure if an antidepressant is working for you...Has it been this long with any of them? Are you on a combo of meds/antidepressants?Your doctor should be monitoring how long you have been on each one,and what,if any,beneficial effects you are getting from them.
Usually it takes a few tries at diferent antidepressants to find the one/ones that work for you,so hang on,there is still plenty of hope and lots of options.Personally I never responded to any antidepressent except for one called Parnate, which is in a class of meds called MAOI's. These have dietary restrictions that MUST be followed,so doctors tend to prescribe them today as a last resort.However, they are extremely effective,often,for very severe,hard to treat depression,and they did save my life...There are always other options out there,I know how easy it is to get discouraged though,and if you are feeling that way now, you might want to tell your doctor you are not yet happy/healthy with your current treatment.There are adjustments and changes he can make--just make sure you are patient with each antidepressant.If you don't feel benefits from your meds now,you really could start to feel them in a few days,or a week---depending on how long you've been on them.Best of luck to you.

I have been on these meds for over a year now and I am on 5 different meds for depression

I am currently taking 50 mg Pristiq, 15 mg Abilify, and .5 mg Clonazepam twice a day as needed. It help me a lot. I still get depress sometimes but it is not like it used to be.

If you feel you are still struggling with your depression,and are not getting enough relief from the medication you are currenly on, please do tell your doctor.A whole year of being on these specific meds does not mean they are all working for you, and it might be helpful to even get a second opinion(from another doctor)about some other antidepressants that you might try.5 antidepressants is a lot to be on at one time; perhaps some are not helping at all,while others could be increased in dosage to help you more.Or:another class of antidepressants could be tried(such as MAOIs, like Parnate or Nardil.) Please talk to your doctor about any changes/improvement in your current meds that you feel still need to be made.The right meds can radically effect your recovery from your depression.

I have failed miserably on most regular anti-depressants, due to they either make me manic or more depressed. I am now on a low dose of Ritalin and am off of the Lamictal and I am starting to feel better. Lamictal helped for a good while, but I tend to be someone who needs a major med change every couple of years or so.

I am also working really hard on exercise and other natural things to do for depression - cognitive too. The meds can only do so much, I have come to believe after many years of this illness.

Exercise is the only definite thing that works for me. I have been on celexa for a while now and doesn't seem to be doing anything except make me feel worse.

HUGS

I am taking Prozac and Wellbutrin. I just recently added 2 mg of Abilify about 3 weeks ago. That was the magic pill for me personally. I feel so much better since taking the Abilify. I am just afraid it will stop working....... The first week starting it was terrible but I am glad I stuck it out. I have terrible anxiety on top of depression and I am happy to say I am in almost complete remission with the anxiety and depression.

Thanks for your responses. I see my doctor tomorrow and I am going to talk to her about everything