I was on meds from the time i was 14-26. i tried several different ones, and none worked for me. i gave the meds up.

Ive been on Lexipro for almost a year but I don't notice a change..

well several things really.... first medication is not a CURE for depression- there are other things you have to do too....

Second- it takes time and a lot of trial and error for you to find the right meds for you- and some give up before they find the right fit in favor of other tools.

Third- The medication I take- I couldn't tell that it did anything for me until I decided to stop taking it with the supervision of my doctor...... I KNEW without a doubt what it had been doing for me then- I describe it as it gives me a bottom- that's it. And frankly I think that's how the meds are supposed to work. I still feel all of my feelings- they just have a bottom now. I'm not numb, I'm not high- I'm just normal. When we get depressed we forget that sometimes you are supposed to feel sad, tired, angry, down, all those things- but we are. We need tools to learn how to handle those feelings before they turn to real honest depression.

Are you working with a gp or a pdoc for your meds? You need a pdoc who really listens and talks with you about what your needs/issues/side effects/problems are.

I am on numerous meds, and still have my bad days.

The medications aren't a cure. But they CAN help. I went through years of therapy and learned to change my unhealthy thinking habits which helped my depression improve tremendously, but did not eliminate it. I still have to take anti-depressants. I feel like a normal person with ordinary ups and downs when the medication is working. When it's not, I have to coach myself through every part of the day.

Unfortunately, I am one of those people for whom anti-depressants have limited effectiveness. Most of them are effective for about a year. So, when one stops working, I have to go on another one. It's very frustrating, because I usually feel bad for a couple of weeks while I am changing over. But once the new one kicks in, I feel like a regular person and can live my life.

There are many kinds of medicines available, and they have different effects. Don't discount them until you've worked with a doctor to find what helps you. Be aware, however, that medication alone won't do it.

I have been on so many differents meds, some worked for a while, then like others, I have had to switch. I have had a lot of weight gain with the meds, or maybe it was the depression, but gained so much weight.

I have been off the meds, the last one Cymbalta for about 2 months. I am going back to the Dr. on the 6th. I just cannot do this on my own.

It is a terrible battle every day sometimes just to hang on. No one understands unless they are going through the same thing. Not fun.

prozac never worked for me.

We are all different. And we are fortunate that there are a lot of choices regarding medications and treatment. If one doesn't work for you, it doesn't mean that all of them won't work for you. It really is trial and error, Still medication alone isn't the answer. It helps to have a little counseling or therapy in addition.