Daliresp is mainly prescribed for the bronchitis component of COPD. It helps with cough and mucus problems and to reduce frequency and duration of exacerbations. So i do not think it helps Emphysema.

COPY:The most common side effects with Daxas (seen in between 1 and 10 patients in 100) are decreased weight, decreased appetite, insomnia (difficulty sleeping), headache, diarrhoea, nausea (feeling sick) and abdominal pain (stomach ache).

Because patients taking Daxas may lose weight, they are advised to weigh themselves on a regular basis. The doctor may stop treatment with Daxas if the patient loses too much weight. For the full list of all side effects reported with Daxas, see the package leaflet.

Take care....Peter

Good point and info qwapo!

Ya know, I forget that COPD covers BOTH emphysema & bronchitis in it's term.
I am sooooo dry with Emphysema that I don't have the phlegm/mucous problem & I flat out forget about the "other" side of this disease.
http://www.healthhype.com/chronic-bronchitis-vs-emphysema-and-difference-in-symptoms.html
(IMO it's kind of dumb "they" put 2 diseases with such opposing symptons under one "umbrella term")
I apologize to those that have the bronchitis side of this dx if I have seemed insensitive to your symptoms!

As for NAC;
It seems like we have had discussions about NAC before (or on another board?).
Some people think it works great & others don't think it works at all. So I assume it is trying it & seeing if it works for you (with Dr approval of course).

I don't know how accurate these are, but there are several sites that you can look up drug interactions
http://www.webmd.com/interaction-checker/
or
http://www.drugs.com/drug_interactions.html
or
http://www.rxlist.com/drug-interaction-checker.htm

Although I do not have a problem with mucus, a few years back I coughed up this alarming-looking "thing." It was so bizarre, I made an appointment to see my pulmonologist. Turns out it was a mucus plug.

My pulmo recommended I take 600 mg NAC twice a day. NAC thins mucus making it easier to cough up.

I know in the past, Mark Mangus, the respiratory therapist who answers questions on the COPD Canada website, has recommended NAC for copd patients who have a mucus problem. I haven't checked that web site in a long time, so I don't know if he continues to recommend NAC.

P.S. There is some concern about the use of NAC and speeding up the growth of lung cancer.

http://www.the-scientist.com/?articles.view/articleNo/39022/title/Antioxidants-Speed-Up-Lung-Cancer/

I advise you talk to your doctor.

Buickoreo;
What symptoms are you trying to relieve with the NAC?
Daliresp & NAC seem to be 2 completely different types of medications.
so really there is no "comparing them" to each other.

from my understanding Daliresp is basically an anti inflammatory type of medication.
As qwapo pointed out;
"DALIRESP (roflumilast) is indicated as a treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with=
chronic bronchitis and a history of exacerbations.
DALIRESP is not a bronchodilator and is not indicated for the relief of acute bronchospasm"
http://www.daliresphcp.com/

NAC is FDA approved to treat overdose of tylenol
It also is supposed to help "loosen thick mucus such as in cystic fibrosis or chronic obstructive pulmonary disease"....INHALED!

https://en.wikipedia.org/wiki/Acetylcysteine
http://www.healthline.com/drugs/acetylcysteine/inhalation-solution#Interactions3

IF you are looking for things to clear mucus here is many ideas on ways to clear it;
http://www.wikihow.com/Clear-the-Throat-of-Mucus

anyway, the two seem to be such different types of medication that when i tried googling "vs" i didn't find much results.
I did find it interesting that in our previous discussions I never noticed the fact that it's only shown to help if Inhaled.
also, it seems NAC sure does have a lot of side effects too!!