This is totally safe! I do this, too. Currently, I take it regularly (350mg) PLUS up to 200 PRN. Last year, for about 6 months, I was well enough that I didn't need it regularly at all, but continued to take up to 400mg PRN.

It does depend on what you are taking it for, though, and the dose. What is it for? Psychosis? If it's for psychosis, you need to take fairly high doese, and if you don't take them regularly, it will knock you out for three days. However, if it's a small dose to take as needed for sleep, then it's totally fine.

How much is your dose and what is it PRN for?

I am not a Doctor but it seems a bit strange to me to order it PRN. I take 400mg twice a day. I know some Docs have their patients take a low dose at bedtime to help them sleep. How much did he order? I think I would check with him again.

small dose really for sleep not even 25 milligrams and I half that.. they seem to make me feel drunk and wanna eat lol...

Oh man, yeah, that's really normal. 12.5 mg PRN for sleep? You'll feel better if you take it every day (because the groggy feeling will wear off after a few days)- on the other hand, if you keep it PRN, that small of a dose will probably lose it's sleep effectiveness rather quickly.

I have done this type of thing (from doses as small as 50 to up to 400mg, like I said). It is safe--but like I said, you might be happier if you do it everyday so you can habituate to the sleepiness.

yea that groggy feeling is a b%$*...
I will talk to my pdoc about it next trip

Ah, 25mg to help you sleep. That makes me feel much better about it. Yes, if you can sleep well on half a dose go for it. If it makes you drunk just don't take it until you are ready to go to bed. It does make you eat a lot. Don't know what to say about that.

I need combination locks on my fridge.. Maybe it will mess me up so I would forget them..
lol

I take 300mg of Seroquel at bedtime and I take 25mg 4 times a day if needed for anxiety.

I have it as and when to stop my hypomania going too far. I've also used it for hypomania related sleep issues.

It makes me fuzzy the next day also.

yea its ok as long as long as you dont take it in high doses and a long time..i took 100 mgs aday for 2 yrs..was realy out of it for about 6 monthes or even more so..it gives you a feeling of withdrawal rebound deppreshion if that makes since to ya....like i had to stop on it due to high h.r. 140 bpm..but im going to see if tommrow when i go if he will give me 25 mgs at night to help sleep..its real GOOD FOR THAT..SO WHEN YOU TAKE IT..U BETTER BE WERE UR GOING TO FALL ASLEEP AT LOL..I WOKE UP IN SO MANNY DIFF PLACES...ALSO IF UR ON 50 MGS OR MORE STAY OUT OF THE SWEETS YOU CAN GAIN..I GAINED 60 POUNDS ON THIS..BUT LOST IT ALL WHEN STOPPED IT GOOD LUCK TO YA JAMES

yes even 25 mgs would put me out..i took a 1/2 25 mgs it made me relax to sleep but took just a hour longer..the truth to ya..if ur pdoc says to take as little as possible do that..100mgs to me was way to much..but theres alot of people on 500mg aday or more even/../ i couldnt even imagine that..i be afraid not to awake..

From an addiction standpoint, I've experienced no problems with it. I did pack on a lot of weight, but it would be unfair to lay it all on the drug.

As to dosage, I take 200mg at bedtime. I take an extra 100mg if I wake up during the night and can't get back to sleep, and 100mg during the day if I'm feeling "fast."

One serious caution I have is that at 200mg l sometimes nod off suddenly and without a lot of warning.

Hey Nick. I'm on 800 mg of seroquel daily for mood swings and it does help. But after talking to my doctor and looking online, this med does not seem to have the withdrawal issues that say, Xanax, has. If your doctor says "as needed" then you should be ok, especially at lower doses. That can be helpful for sleep and mood stabilization. Are you on another medication just for mood stab - like lamictal? That would be a double whammy for you because seroquel is a mood stabilizer. Your doctor may have you on seroquel just for sleep. Call and check in with your doctor about WHY they have you on seroquel and if you have another med that is just for mood stab. My doctor and I have a really good relationship and I can just call to ask questions. You can also check the pharmaceutical company's website - make sure it's the companies and not a consumer. Wish you the best!

Before you take this drug I have two warnings. I was on it for 4 years. I gained tons of weight, because it does make you want to eat. Lots of research behind that - even in small doses.

The other issue which no-one else has mentioned is the possiblity of Tardive Dyskinsia. That is repeated involuntary muscle movements. I had it in my foot with Loxapine, and the pdoc had me quit immediately. Then my daughter started harassing me about all the noise I was making with my mouth, and I had sores all over my tongue, from rubbing against my teeth. I looked it up in the doctor's bible - the Compendium, and it said TD usually starts with the tongue, and it is sometimes irreversible. And sometimes only take one dose - all antispychotics, old, new, typical, anti-typical can do this. I had it for over 2 years, after stopping Seroquel, and my doc put me on MAO's which conflict with every food and drug in the world, and then valium, which finally stopped it, but left me valium dependent.

Usually this condition occurs in middle age women (the perfect description of me!), but it can happen in anyone. So if you really need it, to control mania, or even hypomania, then take it, but there are lots of sleep meds which would be a far better choice if that is the only issue. In Canada we have Imovane, which works really well, but it is not approved in the US, because of pharmacetical wars. So I wouldn't use Seroquel. Get something that puts you under and and doesn't leave you sleepy and drugged the next day.

I would ask around as much as you can, as every one is different in their experience with these drugs.

That being said, I had TD on Abilify (the drug least likely to cause it) but it has minimized to just hand twitches, and occasional tounge twitches.
Also, I have experienced about 20 lbs. weight gain, and I have also slept a little more and had acardia in a minor form. Basically, it just manifests itself in the artieries. That happens to just 6-7% of all the people taking Seroquel.
I currently take 300 mg Seroquel XR and 1000 mg Seroquel instant form.
So, if you need to take Seroquel, come on and jump in. Whether regular or PRN, the water is fine.