I think there are MANY of us here who take seroquel. It has been my favorite of all them I've tried. Yep, weight gain. That's the only part i do NOT like about it.

I'm sure others have more info for you...

I really liked seroquel. I took it about 30 mins before bed and it helped me to fall right asleep! However, I would still wake up around 4 am....but at least I skipped the 2 am wake up. And yes, be prepared for the weight gain, which tends to be dose-dependent. Overall, I was very happy with seroquel, and wasn't thrilled when my new pdoc took me off of it.

For me I hated it. Yes I gained a huge amount of weight and could never find a good dose. I either cycled through it or was comatose.

Really everyone is different and as mentioned many here are taking it.

Good luck whatever you decide.

Talk about gaining weight!!! Not all have that reaction, but I gained 100 lbs. and lost 90 when I got off it. I take trazodone in its place. Now the ambian which I take with it keeps me from driving. I can fall asleep at the wheel!!!! But, I need them both if I want to get any sleep. My depression is pretty good. I am numb. I can laugh, but it takes a lot for me to cry. As far as knocking one out for 10-12 hours, that doesn't happen. I also take other day meds for the depression, PTSD, bi-polar disorder, I have fibro, but I don't take anything for it, cause the only thing out there causes weight gain. So that's a little more than you wanted to know. I would say NO don't take seroquel.

Thanks for the opinions :)

it's a drug that's a bit weird when it comes to sedation... well for me and others have said the same.... I was on 800mg and it was not sedating at all.. I was / am on the XR..... it's just down to 650mg now as I am slowly coming off it.. but it seems the higher the dose the less sedating it is.. again that's for me... years ago I took 125mg of the regular and it knocked me out for 2 hours flat!!

for me it's been a wonderful med

My Seroquel saved me from myself. I still think of it as "my" Seroquel even though I can't take it anymore. The best sleep I've ever had in my life and for me that is key to my stability. It did over sedate me at first but that will pass after a couple of weeks. My only suggestion would be to start a food diary when you start the med. That will just help you be aware of what you are eating and maybe ward off the weight gain. I don't know if it will but I wish I had been forewarned. So easy to put the weight on in three months and it's taken most of this year to take all of it off. Yep, I miss my Seroquel.

Hope it works out well for you.

Thank you all for the advice and support. I plan on trying it this weekend when I have no appointments or plans. I've been on trazodone for 8 years so it's scares me a little to stop taking it. I'm trusting my pdoc though.

I've only been on trazadone for help sleeping. But Seroquel - as an AP - works wonders. My only problem was sleeping too much. I would take it in the morning and be out like a light an hour later, sleeping into the day. My body got used to it though and the heavy sedation stopped. Good luck to you - of course it affects everyone differently - I hope it works for you!