I take this twice a day and it seems to work. I do feel like I am "buzzing" or an electrical current is running through my body for about 15 minutes or so after I take it. It's weird, but not terrible.

i take twice a day. I talke with Effexor

With buspirone I had awful side effects if I didn't take it with a meal, and I don't mean a piece of toast!

I found for nearly 2 hours it would wipe me out, very dizzy, sicky, fatigued and generally like I had been hit by a bus!

SO, yea, take it with a good meal!!

I'm in the same boat as Jonny - I have to take it (and I do 2x a day), but it's extremely hard on me. I get "weirded out", can't function well, get tired, lightheaded (kind of)...it's hard to articulate exactly what's going on, but it's terribly unpleasant. What I get from the meds make it worth taking them, but it sure is rough every single morning and night when the pill kicks in. And yes, do take it with food, or at least some milk - I get seriously sick to my stomach if I don't.

I take 10mg 4 times a day with Paxil. It's okay, but it sure aint XANAX.....

I take it twice a day, three if needed which is rare, now. I tolerate it very well and it helps. It's not a "make the problem go away" kinda med, it's more like a take the edge off so I can realistically deal with the issue kinda med . But it didn't do too much for me until I went on an anti depressant as well.

I take it twice a day along with cymbalta.. It made me sleepy at first but after a few weeks I could tell it helps