I am still trying to get a hold of this problem as well. I am B12 deficient and get injections for that. And was told by my neurologist that I probably will be on the shots the rest of my life. (I have Crohn's disease and have malabsorbtion issues.) I was told by a lot of people I know that they get the B12 shots and they feel so much more energetic. The only difference I see when I get the shots is that my bloodwork gets better...no physical improvements. I also have a ferritin deficiency. My iron comes back in "normal" range but my ferritin doesn't. It has been as low as a "1," in 2010. I can't handle iron pills because they give atrocious side effects not to mention my body just flushes it out it can't absorb it. I get iron infusions occasionally when the numbers get really low but I wish a doctor would look at it more seriously and try to figure out why my numbers only go up a little with each infusion and after a month or more they drop again. With an infusion every couple of months I was going up from 1 and got all the way up to 32 in January 2012. It is now August 2012 and I am back down to a 7. If they don't do something soon I will be back down to 1. I am exhausted, have restless leg syndrome (restless body syndrome more like it), my Crohn's feels it is becoming active, my back is killing me with pain shooting into my right hip, I failed a tilt table test and have been diagnosed with POTS (postural orthostatic tachachardia syndrome), have definiciencys, have Fibromyalgia, etc, etc. All the pain makes me fatigued and then I just have fatigue on top of it. I left work yesterday early because I couldn't keep my eyes open. I had gone down to the clinic (we have an on-site medical clinic) and laid down for 45 minutes and hoped to get back to work after because I had important stuff to finish, but I gave up. There was no way I could get anything done. I came home and slept until this morning. I missed my melatonin so I had nightmares and the restless legs was terrible. I am working on finding the best way to fix and prevent the problems. I go see all my doctors at mayo clinic next week and will talk to them about everything. I'll let you know if I find out anything.

I feel both of your frustrations! If it's not one thing it's another. And the worst of it is the inconsistency AND the doctors apathy towards figuring out the cause~
I'm 50 years old and feel more like 80 sometimes. But just so ya know, Photogrl, if you need to, you can probably go out on disability. I went out for a few weeks for similar reasons. You might want to look into it.
I think people may think I'm a hypochondriac, but I know that my symptoms are as real as anything...just not visible to others.
Good luck to both of you and keep us posted! Nancy

Have you ever been tested for Celiac Disease? Just a quick thought, I am not a expert, but my B12 was on the low side, D was almost nonexistent, and my iron and ferriton leverls were low, absorption rate for iron was at 4%. It was awful, I didnt even know other than I ended up in the hospital with pnuemonia, PE, and I found out there I had anemia. So they sent me to a gastro doc, he tested me for Celiac after extensive "testing". I was not bleeding anywhere that they could find. I even did the camera pill. I was postive for Celiac though. But found out that was why I wasnt absorbing anything very well. After the gluten free diet being started everything absorbed a bit better. I don't think my body has fully recovered on the diet(2 years on diet so far), but my iron levels are better, just the ferriton is low. Immune problems and diseases of different types can go along with Celiac Disease. Sometimes just gluten sensitivity (before it turns into Celiac Disease which is malabsorption )can cause probs with immune system too . The thing is, it saved my son from probably a lot of problems later on. He had problems I noticed after eating breaded food, took him to doc, had a few blood tests done and showed up positive. She sent him to gastro pediatric doc and sure enough he has Celiac disease too. Poor kid inhereited it from me, but in the long run, he may not end up with blood clot or anemia later on in his life.