Addison's Disease Support Group
Addison's disease (also known as chronic adrenal insufficiency, or hypocortisolism) is a rare endocrine disorder. It is estimated that it affects about 1 to 2 in 100,000 people. It occurs when the adrenal glands, seated above the kidneys, fail to produce enough of the hormone cortisol and, sometimes, the hormone aldosterone
Firsts so sorry to those diagnosed with this. I hope it is not my case. But I am sure you folks are the best to help me understand my blood work. Im pasting below. I have all the symptoms that many mention. Some more tangible symptoms (than fatigue, dizzy, emotions etc) are extreme weight loss, nail deformities, and horrible acne/face abscesses. I have a 10 yo, a 3 yo and a 11 mo. I need my life back so badly! I had a partial thyroid removal in 2008. Seems Ive never really been right since, honestly. Anywho, here they are - any thoughts?
Thank you so so much for your time.
ACTH,PLASMA CE = 15 pg/ml ACTH, PLASMA 15 6-50 pg/mL - * 8 AM lab draw
FERRITIN 15 10-154 ng/mL QBA
CORTISOL,TOTAL,LC/MS/MS 12.0 mcg/dL range for 8-10 AM 4.6-20.6 mcg/dL
LH, SERUM 4.6 mIU/mL range for my Mid-Cycle Peak: 8.7-76.3 mIU/mL
FSH, SERUM 7.2 mIU/mL range for my Mid-Cycle Peak: 3.1 - 17.7 mIU/mL
PROLACTIN, SERUM 5.3 ng/mLNon-pregnant: 3.0-30.0 ng/mL
VITAMIN B12, SERUM 396 200-1100 pg/mL
Please note: Although the reference range for Vitamin B12 is
200-1100 pg/mL, it has been reported that between 5 and 10% of
patients with values between 200 and 400 pg/mL may experience
neuropsychiatric and hematologic abnormalities due to occult
B12 deficiency; less than 1% of patients with values above
400 pg/mL will have symptoms.
TSH 1.180 range: 0.450-4.5
T4,Free(Direct) 1.14 range: 0.82-1.77
CBC
WBC 8.0 range 3.5-10.0
RBC 4.37 range 3.78-5.30
HGB 13.8 range 11.7-15.7
HCT 39.8 range 35.1-47.1
MCV 91 range 79-100
MCH 31.6 range 26.0-34.0
MCHC 34.7 range 31.0-36.0
RDW 11.8 range 11.2-15.2
PLT 398 range 140-400
_MPV 8.7 range 5.8-11.0
_NEU 5.8
_LYMPH 1.6
_MONO 0.4
_EOS 0.1
_BASO 0.050
NEUTROPHIL 72.2 range 46.0-77.0
MONOCYTE 5.1 range 0.0-12.0
EOSINOPHIL 1.6 range 0.0-7.0
BASOPHIL 0.6 range 0.0-2.0
LYMPHOCYTE 20.5 range 19.0-47.0
Metabolic Panel
BUN 10 range 6-20
BUN/Creatinine Ratio 16 range 8-20
Calcium, Serum 9.9 range 8.7-10.2
Carbon Dioxide, Total 22 range 18-29
Chloride, Serum 100 range 97-108
Creatinine, Serum 0.62 range 0.57-1.00
eGFR If Africn Am 134 >59
eGFR If NonAfricn Am 116 >59
Glucose, Serum 100 H range 65-99
Potassium, Serum 5.0 range 3.5-5.2
Sodium, Serum 139 range 134-144
Thank you so so much for your time.
ACTH,PLASMA CE = 15 pg/ml ACTH, PLASMA 15 6-50 pg/mL - * 8 AM lab draw
FERRITIN 15 10-154 ng/mL QBA
CORTISOL,TOTAL,LC/MS/MS 12.0 mcg/dL range for 8-10 AM 4.6-20.6 mcg/dL
LH, SERUM 4.6 mIU/mL range for my Mid-Cycle Peak: 8.7-76.3 mIU/mL
FSH, SERUM 7.2 mIU/mL range for my Mid-Cycle Peak: 3.1 - 17.7 mIU/mL
PROLACTIN, SERUM 5.3 ng/mLNon-pregnant: 3.0-30.0 ng/mL
VITAMIN B12, SERUM 396 200-1100 pg/mL
Please note: Although the reference range for Vitamin B12 is
200-1100 pg/mL, it has been reported that between 5 and 10% of
patients with values between 200 and 400 pg/mL may experience
neuropsychiatric and hematologic abnormalities due to occult
B12 deficiency; less than 1% of patients with values above
400 pg/mL will have symptoms.
TSH 1.180 range: 0.450-4.5
T4,Free(Direct) 1.14 range: 0.82-1.77
CBC
WBC 8.0 range 3.5-10.0
RBC 4.37 range 3.78-5.30
HGB 13.8 range 11.7-15.7
HCT 39.8 range 35.1-47.1
MCV 91 range 79-100
MCH 31.6 range 26.0-34.0
MCHC 34.7 range 31.0-36.0
RDW 11.8 range 11.2-15.2
PLT 398 range 140-400
_MPV 8.7 range 5.8-11.0
_NEU 5.8
_LYMPH 1.6
_MONO 0.4
_EOS 0.1
_BASO 0.050
NEUTROPHIL 72.2 range 46.0-77.0
MONOCYTE 5.1 range 0.0-12.0
EOSINOPHIL 1.6 range 0.0-7.0
BASOPHIL 0.6 range 0.0-2.0
LYMPHOCYTE 20.5 range 19.0-47.0
Metabolic Panel
BUN 10 range 6-20
BUN/Creatinine Ratio 16 range 8-20
Calcium, Serum 9.9 range 8.7-10.2
Carbon Dioxide, Total 22 range 18-29
Chloride, Serum 100 range 97-108
Creatinine, Serum 0.62 range 0.57-1.00
eGFR If Africn Am 134 >59
eGFR If NonAfricn Am 116 >59
Glucose, Serum 100 H range 65-99
Potassium, Serum 5.0 range 3.5-5.2
Sodium, Serum 139 range 134-144
I'm sorry that no one has answered you. I don't generally answer questions that have this much medical numbers to go over. I can answer all your symptoms you might have. It also might help to read the post just below yours. She listed her STIM test results and is going on steroids. Reading other posts is always helpful.
Let me know if I can help.
Severe weight loss. I'm 5 ft 8 and 105 and still losing. About 3-4 pounds a month. I'm usually 120. And the post preg weight just fell off. It was a very hard pregnancy. Sick all the time contractions and pre term labor born four weeks early.
Kidney stones. Damn the kidney stones!
Loose stool all the time.
Very strange finger nails. Like beaus lines?
Horrible pshyciatric symptoms.
Splitting headache for three weeks progressively getting worse.
Night sweats
Vomiting at night sometimes
Cramps in abdomin
Yes. My breasts are acting weird. Tmi.
Tremors. Rapid heart beat. Almost like a panic attack.
Very tired and lethargic.
Really no energy or interest or ability to do anything. Includin taking care of my children or working.
Nodule type acne on my face and one in my mouth.
And salt. Must have salt. Got one of those salt lamps and almost licked the dang thing!
My Edno follow up is tomorrow. I'm thinking I should really push a pituitary MRI and stim test? My abdomin ultrasound came back "normal" with a few more kidney stones a renal cyst and a few liver masses that look benign.
Lung X-ray clear. Negative testing for celiac Lyme TB and other culprits.
I just feel like I'm up against a medical wall. And I hate the medical industry so much. None of them really care. Except about their paycheck. :( #endrant
Thanks again. I am reading other posts as much as my head will let me.
Your TSH is fine, but some of your symptoms seem like thyroid. Like the acne on your face. It sounds like your hormones are all over the place. Can you get those tested?
Let us know what the endo says. Your not crazy, it really takes time to dx this disease. I had to ask once a month for 9 months before my primary tested me. For most people getting a dx and treatment started is the hardest part.
Fx for answers.
It isn't unusual to have both your adrenals and thyroid need treatment at the same time. It isn't good to just treat one of the conditions and not the other. You'll feel sicker. Endo's are suppose to test thyroid if they are testing you for adrenal problems. A lot don't. Ask for it.
If the doctor wanted to admit you, you must have been doing badly. Until you start some kind of treatment you should probably go to the hospital if that is what the doctor thinks. If you start steroids you can usually manage from home when your sick. But until then I wouldn't take any chances. Are you having any dizziness?
Good luck on the test.
MRI says no tumor found but gland is mildly heterogeneous.
Stim had baseline of 17 and went to 27 at 30 minutes and 29 at 60 minutes.
And of course my endo goes on vacation for a week and I haven't discussed results and won't until next week. Any insight? Thank you so much!!!!!