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Data were collected until the parturient delivered. The end of the initial epidural injection was recorded as T0. The clinical status of the parturient was assessed at T0?+?30?min, T0?+?1?h and every hour thereafter until delivery. At each of these points, labour pain was assessed by the parturient using a VAS (0�C10) and was recorded by the midwife, who was unaware of the analgesic solution used. The investigators were responsible for administration of additional boluses, and the principal investigator (M. Bo.) was responsible for data collection. http://www.selleck.cn/products/AP24534.html Motor block was evaluated at the end of each stage of labour by the modified Bromage scale, and a positive motor block was defined as a score ��?4. The sensory level was determined by perceived temperature difference to cold spray. Fetal heart rate and uterine activity were monitored continuously throughout labour. Blood pressure, maternal and fetal heart rates were noted at the same observation times as for pain scores. A low systolic blood pressure was defined as a value http://www.selleckchem.com/products/Rapamycin.html http://www.selleckchem.com/products/jq1.html suture. After delivery, the epidural catheter was removed and the patient-controlled device was withdrawn. The total hourly consumption of administered local anaesthetic during labour, the number of boluses administered by the parturient using the PCEA and the number of investigator-administered boluses were noted. The quality of labour was assessed in the subgroup of parturients having had vaginal delivery, by: (i) total duration of labour; (ii) cervical dilation progression slope, calculated from the induction of analgesia to the first observation of full 10?cm dilatation; and (iii) number of hourly observations at full dilatation. Finally, the distribution of the whole duration of labour was analysed in this subgroup and a cut-off value was defined to separate the group of parturients with long labour (between the two observed modalities if binomial, third quartile otherwise). Then, a composite criterion was created from the presence of either caesarean section or long labour.