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4 T does not have any readily demonstrated health risks reflected in vital signs or change in http://www.selleck.cn/products/CAL-101.html cognitive performance. J. Magn. Reson. Imaging 2010;32:82�C87. ? 2010 Wiley-Liss, Inc. ""To compare cross-sectional and in-plane coronary vessel wall imaging using a spiral readout at 1.5 and 3 Tesla (T). Free-breathing coronary vessel wall imaging using a local inversion technique and spiral readout was implemented. Images were acquired in ten healthy adult subjects on a 3T clinical scanner using a 32-element cardiac coil and repeated on a 1.5T clinical scanner using a 5-element coil. Cross-sectional and in-plane spiral vessel wall imaging was performed at both 1.5 and 3T. In cross-sectional images, artifact scores were superior at 1.5T (P http://www.selleckchem.com/products/gsk2126458.html Diffusion-weighted imaging was acquired in 30 patients with breast cancer using seven b-values (0�C800 s/mm2). Three curve-fitting methods were used for biexponential IVIM analysis: a. Direct estimation http://www.selleckchem.com/products/bay-57-1293.html of D (diffusion coefficient), D* (pseudodiffusion coefficient) and f (perfusion fraction) (Method 1), b. Estimation of D first and then D* and f (Method 2), c. Estimation of D and f first and then D* (Method 3). Goodness-of-fit, parameter precision (coefficient of variance [CV]), parameter difference and correlation with relative enhancement ratio (RER) and initial area under the curve (IAUC) from dynamic contrast-enhanced (DCE) MRI of the three methods were determined and compared. Among the three biexponential methods, Method 1 best described most of the pixels (63.20% based on R2; 44.52% based on Akaike Information Criteria). The CV of D calculated from Method 2/3 (14.95%/13.90%), the CV of D* from Method 2 (77.04%) and the CV of f from Method 3 (80.87%) were the lowest among the three methods. Significant difference was observed for each IVIM-derived parameter calculated from all the three methods (P?=?0.000�C0.005). Only the perfusion-related f value calculated from Method 2 was correlated with RER (r?=?0.548; P?=?0.002) or IAUC (r?=?0.561; P?=?0.001). IVIM-derived parameters differ depending on the calculation methods. The two-step fitting method with D value estimation first was correlated with DCE MRI perfusion. J. Magn. Reson. Imaging 2014.