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5% versus 4.2% and 13.0% versus 10.1%, p?=?0.32 for global difference in socio-professional category). As expected, mean duration of disease was significantly longer in patients with POAG than in OHT patients (85?months versus 66.8 months, p=?0.0005). Mean IOP at diagnosis was slightly higher in patients with POAG (25.9 versus 24.1?mmHg, p? http://www.selleckchem.com/products/PD-0325901.html more patients with POAG had an agricultural job during their lifetime (10.7% versus 5.6% in OHT patients). In conditional logistic regression, adjusting for age, gender and duration of the disease, this difference was statistically significant (OR?=?2.57, p?=?0.009). Similarly, more patients with POAG had used pesticides during their professional life (9.0% versus 4.2%, OR?=?2.54, p?=?0.02). By contrast, use of other chemicals during their professional life was not different between POAG and OHT patients (8.4% for both groups). In the 44 subjects who declared professional use of pesticides, the mean duration of pesticide use was 23.9?years (standard deviation 12.3?years, ranging from 2 to 50?years). Of these subjects, 87.8% had used http://www.selleckchem.com/products/3-methyladenine.html insecticides, 85.4% had used herbicides and 61.9% had used fungicides. The small number of exposed subjects did not enable an analysis to be undertaken of the risk of POAG by subcategory of exposure duration or type. With regard to lifestyle factors, regular consumption of fatty fish was lower in patients with POAG (15.3% versus 20.7% consuming fatty fish more than once a week, p?=?0.008), while there was no statistically http://www.selleck.cn/products/Cisplatin.html significant difference in consumption of white fish. Mean consumption of walnuts was 6.6 servings/year in patients with POAG and 10.9 servings/year in OHT patients. Consumption of at least 8 servings/year of walnuts was reported by 19.8% of patients with POAG and 26.2% in OHT patients (OR?=?2.15, p?=?0.003). Consumption of the different types of oils and of supplements or medications containing selenium was not different between patients with POAG and OHT patients. With regard to smoking and drinking, more patients with POAG tended to be past smokers (27.8% versus 17.5% in OHT patients), and were less often current smokers or had never smoked (12.1% versus 15.1%, and 60.1% versus 67.4%, p?=?0.10 for global difference in smoking categories). However, they tended to have smoked more during their lifetime, as reflected by the number of pack-years. Indeed, 11.6% of patients with POAG had smoked 20�C40 pack-years (corresponding, for instance, to 1�C2 packs/day for 20?years) versus 8.7% of OHT patients; 6.