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Forty-six http://www.selleck.cn/products/incb024360.html participants were randomized to a control group or an 8-week adapted yoga group that followed a standardized protocol with weekly classes and home practice. Medical and psychosocial data were collected at baseline and follow-up, then compared and analyzed. Total shock anxiety decreased for the yoga group and increased for the control group, t(4.43, 36), P http://www.selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html firings at end of follow-up. Our study demonstrated psychosocial benefits from a program of adapted yoga (vs usual care) for ICD recipients. These data support continued research to better understand the role of complementary medicine to address ICD-specific stress in cardiac outcomes. Clear and convincing clinical evidence has established that living with an implantable cardioverter defibrillator (ICD) http://www.selleckchem.com/products/bmn-673.html saves patients�� lives. In a 1999 landmark trial comparing the ICD to antiarrhythmic drugs, the ��ICD remains superior��in prolonging survival after life-threatening arrhythmia.��[1](p.1552) Concomitantly, psychosocial research on the ICD has shown that living with the device as a treatment for life-threatening arrhythmias can lead to further/increased anxiety, isolation, hostility, and depression.[2, 3] The typical ICD recipient must overcome both the stress of life-threatening arrhythmias and the challenge of adjusting to the device, with 13�C46% of patients experiencing anxiety symptoms and 24�C46% of patients experiencing depressive symptoms.[4-7] Clinical trials have demonstrated that psychological stress can have deleterious effects on the heart. Psychological stress has been shown to be a risk factor following myocardial infarction for ischemic complications, reinfarction, mortality, and in-hospital complications. Psychological stress adversely affects cardiac risk factors and disease states, including the equilibrium of the autonomic nervous system and vagal control, which leads to increased incidence of significant ventricular tachyarrhythmia.