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The 204 alternative living donor transplantations were via the donor-exchange (41), the altruistic donor (71), the domino-donor (49), and the ABO incompatible donor transplantation programs (43). Pre-emptive transplantations were performed in 179/889 (20.1%) LD recipients, and in 6/535 (1.1%) deceased donor (DD) recipients. In the period studied 899 patients had not been transplanted (NT): 435 were still on the waiting list, 244 patients were delisted without a renal transplantation and 220 patients died while on the waiting list (Fig.?1). Of all http://www.selleckchem.com/products/z-vad-fmk.html patients enlisted, 20% had subsequently been delisted without a renal transplantation. Table?1 shows the prevalence of ABO blood type O in the populations studied. Blood type O recipients are underrepresented in both living and deceased donor kidney transplantation populations compared to the population NT. The ABO blood type distribution of the populations is shown in Figure?2. In the donor-exchange program the prevalence of blood type B was higher than in the population NT (11/42, 26.2%, P?=?0.042). In all other transplanted populations the prevalence of blood type B was not significantly different from the population NT. Table?2 shows waiting times from the various populations according to ABO blood type. In the DWT, and in the WL population there is a significant difference in waiting time between patients with blood types O and A, but not between patients with blood types O and B. In the DD transplantation population blood types O and B recipients waited significantly longer than blood types A and AB recipients. http://www.selleckchem.com/products/ly2157299.html From the population of blood type O deceased donors only 86.7% of kidneys had been allocated to O recipients and 13.3% had been allocated to non-O recipients. Via the AM program 42.6% (20/47) of O-donor kidneys had been allocated to non-O recipients, in the non-AM population this was 6.4% (13/202). In the population of recipients of a direct living donor 38.1% of blood type O kidneys had been transplanted to non-O recipients. Highly sensitised patients are not underrepresented in the population T compared to the population NT (Table?1). The DWT and the WL populations http://www.selleck.cn/products/s-gsk1349572.html had comparable percentages of highly sensitised patients (Fig.?3). However, there were significantly more sensitised patients (PRA 5�C85%) in the former population [34.3% (159/464) respectively 21.6% (94/435) Fig.?3, P?