Ulcerative Colitis Treatment Reduces Need For Surgery By Almost Half

Should I have surgery to cure ulcerative colitis?

TNF is a chemical messenger and a key part of the immune reaction. Infliximab blocks the action of TNF by preventing it from binding to its receptor in the cell. Ulcerative colitis usually affects only the inner lining of the large intestine (colon) and rectum. It usually occurs in a continuous stretch of the colon, unlike Crohn's disease, which occurs in patches anywhere in the digestive tract and often spreads into the deeper layers of affected tissues. Each year, Mayo Clinic physicians treat more than 2,000 people with ulcerative colitis. For more information on treatment for ulcerative colitis at Mayo Clinic, please visit: http://www.mayoclinic.org/ulcerative-colitis/ . Mayo Clinic's Division of Gastroenterology and Hepatology has been ranked #1 in the U.S. News & World Report Honor Roll of Top Hospitals since the rankings began 20 years ago. Dr. Sandborn provided consulting services for Centocor during the course of this research and received no personal compensation. Mayo Clinic received reimbursement for the services provided by Dr. Sandborn. About Mayo Clinic Mayo Clinic is the first and largest integrated, not-for-profit group practice in the world. informative post http://www.newswise.com/articles/ulcerative-colitis-treatment-reduces-need-for-surgery-by-almost-half

Instead, there's an experimental therapy available. "What we think is happening with this medication is that it's promoting healing of that inflamed lining of the bowel," said Sandborn. MDX-1100 works by blocking a protein called chemokine, clearing it from the body so inflammation can't occur. Current drugs can hinder the immune system, lead to infection and even increase the risk of cancer. MDX-1100 promotes healing. "It seems to be really targeting the colon, so it leaves much of the rest of the body alone," said Sandborn. But if they stop the therapy, symptoms will come back. Patients get an infusion of the drug about every four weeks. So far, it's shown good results in a Phase One study. It's now in Phase Two of testing. One interesting fact: smoking actually protects patients from ulcerative colitis. Smokers have about half the risk of developing the disease compared to nonsmokers. Related Content More: Healthy Living home page STOP SUFFERING IN SILENCE: HOPE FOR ULCERARATIVE COLITIS ULCERATIVE COLITIS: Ulcerative colitis is a type of inflammatory bowel disease (IBD) that affects the lining of the large intestine (colon) and rectum. The cause of this disease is unknown. However, patients who have this disease generally have a weaker immune system. webpage http://abclocal.go.com/kabc/story?id=8578237

New ulcerative colitis drug alternative to surgery

Medical Information What is ulcerative colitis? Inflammatory bowel disease (IBD) is a group of disorders that cause inflammation or ulceration of the digestive tract . The most common forms are ulcerative colitis and Crohn's disease. Ulcerative colitis affects the colon and the rectum. It can cause abdominal pain, diarrhea or constipation, and bleeding. In some cases, symptoms may develop in other areas of the body, such as the joints, the eyes, and the skin. How is ulcerative colitis treated? In many mild cases, medicines can reduce the inflammation and manage the symptoms. But medicines sometimes do not work. Surgery to remove the colon (total colectomy) is the only cure. What are the long-term risks of having ulcerative colitis? our website http://www.webmd.com/ibd-crohns-disease/ulcerative-colitis/should-i-have-surgery-to-cure-ulcerative-colitis