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The median age and body weight of these seven patients at LDLT were 2?months (range 0�C14?months) and 3.2?kg (range 2.6?kg�C12.4?kg), respectively. The median postoperative day (POD) on which dialysis was started was POD1 (range POD1�C4) and the median duration of dialysis was 4.9?days (range 1�C8?days). The median proportionate increase in body weight after LDLT compared with that before was 23.1% (range 4.8�C32.1%). The median proportionate reduction in body http://www.selleckchem.com/products/bay80-6946.html weight after dialysis compared with that before was 11.8% (range 7.9�C23.0%). The median PaO2/FiO2 (P/F) ratio before and after dialysis was 159 (range 58�C247) and 339 (range 245�C511), respectively (P? http://en.wikipedia.org/wiki/MYO10 very low body weight (4.5�C7.5?kg) and how to deal with them in this specific patient http://www.selleckchem.com/products/poziotinib-hm781-36b.html or donor population (21), our experience in the present series indicated that apheresis and dialysis for neonates was able to be performed. In the preoperative management of pediatric LDLT, apheresis and dialysis are an indispensable procedure that can act as bridging therapy before LT for ALF, renal replacement therapy for ARF, or treatment of hyperammonemia due to congenital metabolic diseases and can facilitate antibody removal in cases of ABO-incompatible LDLT. Pediatric ALF is characterized by severe encephalopathy, coagulopathy, and subsequent multiple organ failure, resulting in a high death rate. Apheresis and dialysis for ALF are extremely effective for preventing life-threatening bleeding while maintaining an appropriate volume status in small children. However, apheresis and dialysis for ALF in pediatric patients are merely bridging therapies before LT if this treatment has no effect on the neurologic complications and has no impact on the ability of the liver to regenerate, and LT is ultimately considered to be the best option, with long-term survival rates exceeding 80% (6).
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