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The aim of this study was to evaluate the effects of lanthanum carbonate on the progression of VC in HD patients with type 2?DM. We conducted a randomized controlled trial comparing LC with calcium carbonate (CC) in 43 HD patients at a single dialysis center. Estimations of aortic calcification index (ACI) by abdominal computed tomography were performed twice for each patient (at baseline and 12 months). Forty-one patients completed the study (19 LC, 22 CC). When ACI at baseline was �Q0.48 (median of baseline ACI), median change in ACI (��%ACI) was 20.44 (11.50�C36.80%) in the LC group, and 40.00 (33.30�C92.60%) in the CC group (P?=?0.026). On the other hand, when ACI at baseline was >0.48, the median change http://en.wikipedia.org/wiki/MYO10 in ACI (��%ACI) was 6.42 (3.13�C24.40%) in the LC group, and 8.08 (5.68�C12.20%) in the CC group (P?=?1.000). Serum markers of chronic kidney disease-mineral and bone disorder (CKD-MBD), HbA1c, dose of vitamin D analogues, and side-effects of medications did not change in either group throughout the study except int-PTH increased in the LC group. This study indicated that administration of LC inhibited the progression of VC in patients receiving HD for type 2?DM, only in cases of slight VC compared with CC. ""Measurements of dialysate sodium are used to estimate peritoneal dialysis sodium losses and sodium sieving, a measure of hydraulic permeability of the peritoneum. Peritoneal dialysates differ from serum samples in terms of pH, osmolality, protein and glucose concentration. We wished to determine whether these factors affected sodium measurement. Dialysate samples were http://www.selleckchem.com/products/bay80-6946.html taken from 52 consecutive peritoneal dialysis patients http://www.selleckchem.com/products/poziotinib-hm781-36b.html attending for a standard peritoneal dialysis equilibrium test (PET), 20 with standard lactate dialysate and 32 with neutral pH dialysate and sodium was measured by both flame photometry and indirect ion selective electrode (ISE). Sodium measured by ISE consistently overestimated that measured by flame photometer, mean bias 1.5?mmol/L (95% confidence limits 1.2 to 1.8), P?