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""OBJECTIVES: To estimate trends in the prevalence and comorbidities of http://www.selleckchem.com/products/ABT-737.html diabetes mellitus (DM) in U.S. nursing homes from 1995 to 2004. DESIGN: SAS callable SUDAAN was used to adjust for the complex sample design and assess changes in prevalence of DM and comorbidities during the study period in the National Nursing Home Surveys. Trends were assessed using weighted least squares linear regression. Multiple logistic regressions were used to calculate predictive margins. SETTING: A continuing series of two-stage, cross-sectional probability national sampling surveys. PARTICIPANTS: Residents aged 55 and older: 1995 (n=7,722), 1997 (n=7,717), 1999 (n=7,809), and 2004 (n=12,786). MEASUREMENTS: DM and its comorbidities identified using a standard set of diagnosis codes. RESULTS: The estimated crude prevalence of DM increased from 16.9% in 1995 to 26.4% in 2004 in male nursing home residents and from 16.1% to 22.2% in female residents (all P http://www.selleck.cn/products/Methazolastone.html impairment showed a significant increasing trend in DM (all P http://www.selleckchem.com/products/Nutlin-3.html 1995. This could be due to increasing DM prevalence in the general population or to changes in the population that nursing homes serve. Nursing home care practices may need to change to meet residents' changing needs. Diabetes mellitus (DM) is the sixth leading cause of death in the United States.1 The attributable economic effect of DM exceeded $174 billion in 2007.2 DM prevalence has increased substantially in the United States, with the largest absolute increases observed in those aged 65 and older.3 In 2007, 23.6 million people, or 7.8% of the U.S. population (23.1% of those aged ��60), had DM (diagnosed or not).4 In the Medicare population, the annual incidence of DM increased 23%, and prevalence increased 62% between 1994/95 and 2003/04.5 Moreover, in addition to microvascular and macrovascular complications, DM in older adults is associated with cognitive disorders, physical disability, falls and fractures, and other geriatric syndromes.6�C10 The increasing burden of DM in older adults raises the question about its effects in long-term care settings such as nursing homes. The increasing life expectancy and the potentially escalating demand from the country's baby boomer population could pose future challenges for nursing homes. Although growing postacute care in nursing homes and increasing nursing home alternatives (e.g.