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These patients were followed until death, loss of follow up or survival until June 30, 2007, as recorded http://www.selleck.cn/products/wnt-c59-c59.html in the SRTR and DaVita databases. Among the 14 632 observed waitlisted MHD patients with a median follow-up time of 907 days, there were 5060 deaths (35%). Table 1 compares the demographic, clinical and laboratory characteristics of the 14 632 wait-listed MHD patients in the 6-year DaVita cohort across the BMI categories. Higher BMI was associated with older age, higher prevalence of diabetes and higher serum creatinine level. As shown in Table 1, the crude mortality was lowest in the highest BMI category (>35 kg/m2). Using the Cox regression model to calculate death HR before adjustment and after adjustment for case-mix and additional MICS variables, each one kg/m2 increase in BMI was associated with a death HR (and 95% confidence interval) of 0.96 (0.95�C0.96), 0.95 (0.94�C0.95) and 0.96 (0.95�C0.97), respectively (p 35 kg/m2 group had a 40% lower http://www.selleckchem.com/products/BI6727-Volasertib.html death risk after adjusting for both case-mix and MICS variables (p http://www.selleckchem.com/products/cb-839.html serum creatinine with the waitlisted risk of death is shown in Figure 3 and Table 3. As shown in Table 3, compared to lowest adjusted serum creatinine quintile (reference), the case-mix and MICS adjusted death risk in wait-listed MHD patients with the 4th and 5th quintiles of adjusted serum creatinine were 25% and 43% lower (p