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Survival rates were estimated by the Kaplan�CMeier method and compared by the log rank test with graft failure and patient death as events. Multivariate logistic regression analysis was used to identify potential risk factors for DGF. All tests were two-tailed and P-values https://www.selleck.cn/products/incb024360.html from 2005 to 2010 is presented in Fig.?1. Analysis of Kaplan�CMeier survival curves showed overall and death-censored graft survival rates were 96.6% and 96.6% at 3?months, 94.6% and 96.6% at 1?year, 90.7% and 92.6% at 3?years, and 84.6% and 92.6% at 4?years, respectively (Fig.?2). Five renal grafts were lost during the post-transplant follow-up, one because of renal vein thrombosis, one secondary to the relapse of HIV infection in the allograft and three others because of patient deaths. Mean follow-up of patients was 26.5?months (range: 0.5�C62?months). Patient survival rates at 3?months, 1, 3, and 4?years were 98.3%, 96.3%, 96.3%, and 90.3%, respectively (Fig.?3). Three patients (5.1%) died during follow-up, one because of acute myocardial infarction https://www.selleckchem.com/products/cobimetinib-gdc-0973-rg7420.html 24?h postoperatively and other two because of broncho-pneumonitis caused by CMV and Aspergillus infection at 5 and 41?months. No PNF grafts were observed in this series. Two recipients were excluded from the analysis of DGF rates, because one died 24?h post-transplant and it remain unknown whether the graft was functioning at the time of patient https://www.selleckchem.com/products/bmn-673.html death, the other lost the kidney graft because of renal vein thrombosis. Twenty-six of 57 patients (45.6%) experienced DGF. The occurrence of DGF did not adversely influence graft survival, as overall graft survival rates were 100%, 95%, 95%, and 83.1% for patients with DGF compared with 100%, 100%, 91.7%, and 91.7% for patients without DGF at 3?months, 1, 3, and 4?years, respectively (P?=?0.52, Fig.?4). In addition, DGF did not increase the risk of acute rejection or surgical complications: among 26 recipients with DGF, 8 (30.7%) developed acute rejection compared with 8 (25.8%) recipients without DGF (P?=?0.67). The rate of all surgical complications was 34.6% and 25.8% in recipients with and without DGF, respectively (P?=?0.46). The use of HMP (n?=?10) was associated with a nonstatistically significant lower rate of DGF in comparison to that of SCS (30% versus 48.5%, respectively, P?=?0.31).