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Fast-SENC circumferential and longitudinal RV shortening correlated closely with SENC measurements (r = 0.86, r = 0.90, P http://www.selleck.cn/products/Paclitaxel(Taxol).html hypertension patients (?18.06 �� 3.3 versus ?21.9 �� 1.9, P http://www.selleckchem.com/products/pirfenidone.html ultrasound (MR-HIFU) is a noninvasive technique for depositing thermal energy in a controlled manner deep within the body. However, the MR-HIFU treatment of mobile abdominal organs is problematic as motion-related thermometry artifacts need to be corrected and the focal point position must be updated in order to follow the moving organ to avoid damaging healthy tissue. In this article, a fat-selective pencil-beam navigator is proposed for real-time monitoring and compensation of through-plane motion. As opposed to the conventional spectrally nonselective navigator, the fat-selective navigator does not perturb the water�Cproton magnetization used for proton resonance frequency shift thermometry. This allows the proposed navigator to be placed directly on the target organ for improved motion estimation accuracy. The spectral and spatial selectivity of the proposed navigator pulse is evaluated through simulations and experiments, and the improved slice tracking performance is demonstrated in vivo by tracking experiments on a human kidney and on a human liver. The direct motion estimation provided by the fat-selective navigator is also shown to enable accurate motion compensated http://www.selleckchem.com/products/Maraviroc.html MR-HIFU therapy of in vivo porcine kidney, including motion compensation of thermometry and beam steering based on the observed three-dimensional kidney motion. Magn Reson Med, 2011. ? 2011 Wiley-Liss, Inc. ""A novel method for B mapping based on the Bloch-Siegert (BS) shift was recently presented. This method applies off-resonant pulses before signal acquisition to encode B1 information into the signal phase. BS-based methods possess significant advantages in measurement time and accuracy compared to magnitude-based B methods. This study extends the idea of BS B mapping to Carr, Purcell, Meiboom, Gill (CPMG)-based multi-spin-echo (BS-CPMG-MSE) and turbo-spin-echo (BS-CPMG-TSE) imaging.