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Based on the number of positive cores, the rate of extraprostatic disease was 11.7% and 23.3%, respectively, in the low-and high-risk GS ��3?+?3 groups (P? http://www.selleckchem.com/products/bmn-673.html and high-risk GS 3?+?4 patients. Univariable and multivariable intergroup BCR rate differences were statistically significant between low- vs high-risk GS 3?+?3 patients (P? http://www.selleckchem.com/products/pexidartinib-plx3397.html and white blood cell count). We computed a score relating to the severity of the disease at the time, and compared it to other features according to whether the patient survived or died. The different prognostic factors were assessed by univariate analysis with the Mann�CWhitney U and Kendall A-B tests. Of the evaluated 51 inpatients, eight died (16%) and 43 survived (84%). The median (range) age was 63 (17�C85)?years and the median time from the onset of the symptoms until the admission to the emergency room was 7.8 (1�C60)?days. The mean hospital stay was 33 (2�C90) days and 17 patients were admitted to the intensive-care unit for a mean of 4.5?days. There was no statistically http://www.selleck.cn/products/nlg919.html significant difference between the groups. Body surfaces involved were the scrotum in five patients (10%), the penis and scrotum in 11 (22%), the scrotum and perineum in 30 (59%) and the abdominal wall in five (10%). There was no statistically significant difference in the distribution in those who survived or died (P?=?0.131). The median age of 60?(17�C81) years in the survivors was significantly lower than that of 73.5? (50�C85)?years in those who died (P?=?0.02). There was no significant difference (P?=?0.06) between the number of repeated debridements in the survivors (3.23) and those who died (5.25). The mean (range) FGSI score for survivors was 6.7?(0�C14), vs 8.7?(6�C13) for those who died (P?=?0.12).