The Role o f Human Coactosin - Like Protein i n Neurodegenerative Disorders

Coactosin is one of the numerous actin binding proteins which regulate the actin cytoskeleton. Coactosinbinds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Coactosin and human coactosin like protein 1 (COTL1) have the potential to play a role in the degradation or impairment of neuronal cells and their functioning. Its homology to other proteins that affect neuronal cells also contributes to this notion. The objective of this review is to explore its structural novelty, regulation and its significance in neurodegenerative diseases


 


The study of chemical processes within and relating to living organisms is known as Biochemistry. This may sometimes be called as Biological chemistry. The complexity of life can be explained using various biochemical processes.