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The hypothesized model provided a good fit in the full sample (��2?=?409.06; d.f.?=?91, p? http://www.selleckchem.com/products/ABT-737.html fit index (CFI)?=?0.98; standardized root mean residual (SRMR)?=?0.04) and the accelerometer subsample (��2?=?320.96, d.f.?=?134, p? http://www.selleckchem.com/products/Nutlin-3.html survival [10]. Physical activity is one lifestyle factor that has been shown to have significant QOL benefits for breast cancer survivors and has also been associated with enhanced survival and reduced risk of recurrence and mortality [11-14]. Although there is a substantial body of literature supporting beneficial effects of regular physical activity on QOL in breast cancer survivors [14], the mechanisms underlying this relationship are not well understood. One of the major reasons for a lack of knowledge regarding such mechanisms may be the conceptualization of QOL in the cancer literature. The majority of studies examining http://www.selleck.cn/products/Methazolastone.html physical activity and QOL in the breast cancer literature have focused solely on HRQOL [15], adopting the traditional medical literature's characterization of QOL as an ��umbrella term�� under which a broad array of health status and disease outcomes reside. Few studies have classified QOL as a global psychological construct reflecting a ��conscious cognitive judgment of one's current satisfaction with one's life��, or life satisfaction [16]. Although health status may be associated with global measures of QOL, these constructs are conceptually and theoretically independent [17, 18], limiting the focus on QOL to an umbrella term for multiple constructs limits theory development, understanding of variability and changes in QOL, and knowledge about the meaning of HRQOL and health status for cancer patients and survivors [19, 20].