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001 for ��2 differences between categories within each group). Drug dispensation was directly correlated with the frequency of comorbid conditions; those with four or more comorbid conditions were dispensed treatment significantly more often (54%) when compared with those with fewer comorbid conditions http://www.selleck.cn/products/gsk-j4-hcl.html (P? http://www.selleckchem.com/products/BEZ235.html logistic regression model included the variables dementia http://www.selleckchem.com/products/byl719.html status, age, sex, fracture status, comorbidity and residence (health region); all variables were statistically significant; therefore, all were retained in the final model. There were statistically significant interactions between the following factors: (i) dementia status and sex (P?=?0.059); (ii) dementia status and comorbidity (P?=?0.001); (ii) dementia status and fracture status (P?=?0.057); and (iv) dementia status and residence (health region) (P?=?0.008); therefore, these interaction terms were retained in the final model. After controlling for age, sex, fracture status, comorbidity and residence, a diagnosis of dementia was found to be a significant negative predictor of osteoporosis drug dispensation (adjusted OR 0.59; 95% CI 0.47�C0.75). Male sex was the strongest negative predictor of osteoporosis drug dispensation; males were seven times less likely to have been dispensed treatment than females (adjusted OR 0.14; 95% CI 0.13�C0.15). Increasing age was associated with a significant decrease in the likelihood of being dispensed an osteoporosis drug when compared with younger patients.