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Paediatric trauma patients were further analysed in four subgroups ( http://www.selleckchem.com/products/ch5424802.html in the TC. Secondary end-points were the proportion of trauma victims arriving in the TC with ISS??15, time from dispatch of the first ground EMS to arrival at the TC, ISS, LOS, and 30-day mortality. Continuous data are reported as medians with interquartile range (IQR) and compared with Wilcoxon rank-sum-test or Kruskal�CWallis test where appropriate. Categorical data are reported as counts with percentages (%), and 95% confidence interval for mortality rates where appropriate. Groups were compared with Fisher's exact test or ��2 test where appropriate. Data analysis was performed using SPSS Statistics 20.0 (IBM Corp., Somers, NY, USA). P? http://www.selleckchem.com/products/VX-770.html Permissions from the Danish Data Protection Agency (j. no: 2009-41-4122) and the National Board of Health (j. no: 7�C604-04-2/128/HKR) were obtained prior to the study. According to Danish law, neither informed consent nor approval from the ethics committee was required for this study. A total of 1934 trauma patients were included in this study (Fig.?1), with 238 paediatric (12.3%) and 1696 adult (87.7%) patients (Table?1). A total of 18/238 children (7.6%) vs. 184/1696 adults (10.8%) were transported directly to the TC from the accident site, and 220/238 children (92.4%) vs. 1512/1696 adults (89.2%) directly to a local hospital (P?=?0.14) (Fig.?2). Air transport was used in 16/238 children (6.7%) and 152/1696 adults (9.0%). Interhospital transfer to the TC occurred in 15/220 children (6.8%) and 120/1512 adults (7.9%); thus, a total of 33/238 children http://www.selleck.cn/products/Verteporfin(Visudyne).html (13.9%) and 304/1696 adults (17.9%) arrived at the TC post-injury (P?=?0.14). Paediatric trauma patients transported to the TC were significantly less injured than the corresponding adult trauma patients [median ISS 9 (IQR: 1�C15) vs. 14 (IQR: 5�C25), respectively, P??15, was found in 11 children and in 182 adults. There was no significant difference between the groups in the proportion of seriously injured trauma victims taken to the TC [8/11 (72.7%) vs. 139/182 (76.4%)]. The corresponding figures for ISS??15 was significantly less common in children transported to the TC (8/33, 24.2%) compared with adults (139/303, 45.9%) (P?=?0.02). Interhospital transfer of patients with ISS?