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The aim of this study was to describe six cases of acute cataract in adolescents at the onset of type 1 diabetes. Eight hundred and twenty-six patients with type 1 diabetes were retrospectively studied. A multivariate analysis was applied to verify the weight of the following laboratory findings taken on admission (independent variables): glycemia, glycated hemoglobin (HbA1c), pH, base excess (BE),and on the occurrence of cataract (dependent variable). Six patients (0.7%) presented http://www.selleck.cn/products/BKM-120.html with acute lens opacities. Cataract development was significantly correlated with HbA1c and glycemia. The relative risk increases about twice for each percentage point from 12.8 to 14.1% of HbA1c; glycemic blood levels represent a moderate risk factor for cataractogenesis. Ketoacidosis http://www.selleckchem.com/products/Y-27632.html and BE were not significantly correlated. ""To investigate whether center differences in glycemic control are present in prepubertal children http://www.selleckchem.com/products/chir-99021-ct99021-hcl.html p?=?0.179). Language difficulties showed a negative relationship with HbA1c (8.3?��?1.2% vs. 8.0?��?1.0%; p = 0.036). Frequency of blood glucose monitoring demonstrated a significant but weak association with HbA1c (r?=??0.17; p?