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0349?��?0.0030 vs. 0.0309?��?0.0031?cmH2O/ml/s). Dynamic P�CV curves were obtained in both groups (Fig.?2a and b). In the surfactant group, the total lung volume at the http://www.selleckchem.com/products/ly2157299.html same pressure of 30?cm H2O was more than that in the control group. In the control group, nothing was visible within alveoli (Fig.?3a). On the other hand, in the surfactant group, hollow-round or small-round brown particles were lining in contact with the alveolar wall within well-inflated alveoli (Fig.?3b and c). The body weights of the rats were similar in all three groups (299?��?9.5?g, 300?��?5.5?g, and 299?��?9.8?g in the sham, control, and surfactant groups, respectively). All the lungs were reperfused successfully in 80?min. Thus, consistent http://www.selleckchem.com/products/z-vad-fmk.html with previous reports [12�C17], our isolated rat lung perfusion model remained stable throughout the observation period. Airway resistance in the control group increased and was significantly higher than that in the sham group (P? http://www.selleck.cn/products/BIBW2992.html group was low and increased gradually. Shunt fraction in the control group increased and was significantly higher than that in the sham group (P?