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O092 ELETRICAL AND MECHANICAL ATRIAL REMODELING PREVENTION USING MINIMAL VENTRICULAR PACING AND RIGHT OUTFLOW TRACT VENTRICULAR LEAD IN SINUS NODE DISEASE Menezes A Jr; Carneiro ARC; Oliveira BL; Souza LA; Neto WJS Catholic University of Goias Introduction: Will the minimum ventricular stimulation of the pacemaker when associated with alternate ventricular stimulation site reduce the incidence http://www.selleck.cn/products/z-vad-fmk.html of Permanent or Intermittent Atrial Fibrillation (AF) in long-term?Objectives: Compare the synergetic effects of the minimum ventricular stimulation management (IRS PLUS) and right ventricular outflow tract (RVOT) stimulation in sick node syndrome (SND) patients in electrical and mechanical atrial remodeling to RVOT stimulation alone. Methods: 50 SND patients were submitted to a dual chamber pacemaker implantation. The atrial leads were positioned in the right atrium septum and the ventricular lead in the right outflow tract. Patients were randomized in two groups, GROUP I (IRS plus ON in the first 6 months, then the next 6 months the IRS PLUS was turned OFF, then again turned ON for the next 12 months) e Group II (exact the opposite sequence of group I). After 6, 12, 18 and 30 months all patients were submitted to: 1) Follow-up, 2) Pacemaker telemetry of the AF burden and Mode Switches 3) Transesophageal Echo and 4) Completion of SF-36 form. Results: All data were calculated using the Mann-Whitney Test 1)? AT- AF burden in IRS Plus OFF was higher in all http://www.selleckchem.com/products/dabrafenib-gsk2118436.html evaluations (6, 12, 18 and 30 months)- p http://www.selleckchem.com/products/sch772984.html with right ventricular outflow tract stimulation reduced the AF burden and left atrium remodeling due to a lower incidence of Atrial Fibrillation in 30 months follow-up. SUDDEN CARDIAC DEATH O093 ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA: CLINICAL POLYMORPHISM AND THE ROLE OF ACCOMPANYING MYOCARDITIS Blagova OV; Nedostup AV; Morozova NS; Kogan EA; Gagarina NV; Sedov VP; Shestak AG; Zaklyazminskaya EV; Frolova YuV; Dzemeshkevich SL I.M.Sechenov I Moscow State Medical University, B.V.Petrovsky Russian Scientific Center of Surgery Objective: To study clinical polymorphism of arrhythmogenic right ventricular dysplasia (ARVD), prevalence and a role of accompanying myocarditis. Methods: We did observe group of 15 patients (9 females; 6 males, 45,5 �� 15,9 y.o.) with clear (n = 9) and suspected (n = 6) diagnosis of ARVD. Investigations included heart CT/MRI; PCR detection of virus genomes, anti-heart antibodies (AB); one right ventricle (RV) biopsy; and 2 autopsy. Genetic analysis is in progress now for all patients. Results: Three variants of ARVD phenotypes were sorted out. Group 1, ��Typical�� (or ��latent arrhythmic��, n = 8; 44.5 �� 12.9 y.o.), with frequent persistent ?idiopathic? premature ventricular beats from RV, nonsustained ventricular tachycardia (VT); lack of major ECG criteria in the presence of intra-myocardial fat.