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91 [95% CI 1.14�C3.22]). Bradycardia occurred in one diabetic and in three nondiabetic dogs (Table?2). Hypothermia occurred in 34 (52%) diabetic dogs and 35 (55%) nondiabetic dogs (Table?2). The overall incidence of severe hypothermia was 3% with zero diabetic dogs and four nondiabetic http://www.selleck.cn/products/ON-01910.html dogs being affected (Table?2). Twenty-nine (44%) of diabetic dogs had at least one episode of severe hyperglycemia while anaesthetized. Cardiac arrhythmias were not reported in any dog of either group (Table?2). There was no significant difference in the frequency of postoperative systemic (P?=?0.7) or ocular complications (P?=?0.6) between the two groups (Table?2). No dogs in either group died during general anesthesia or during the immediate postoperative period. Anesthetic complications occurred in 59% of diabetic and 33% of nondiabetic dogs. In agreement with previous studies, hypotension was the most common complication occurring in 71% of diabetic and 63% of nondiabetic dogs, however, hypotension occurred more frequently than previously reported.16,20,22 The discrepancies between studies may be in part due to differences in definitions of hypotension and methods of measuring blood pressure. Although hypotension was defined as MAP http://www.selleckchem.com/products/abc294640.html phacoemulsification, documented a complication only if it was present for at least 10?min, which could account http://www.selleckchem.com/products/loxo-101.html for the apparent lower incidence.16 Direct arterial blood pressure measurement is more accurate than indirect, noninvasive techniques.23,24 In this and in previous studies, a combination of direct and indirect methods of blood pressure measurement was used which makes comparison between studies difficult. Consistent measuring of blood pressure by invasive methods would have ensured absolute accuracy in determining the presence of hypotension in this study. However, multiple publications have demonstrated the accuracy of noninvasive blood pressure monitoring for detecting hypotension in anesthetized dogs.23�C25 The explanation for the increased incidence of moderate and severe hypotension in diabetic dogs may relate to their relatively hyperglycemic status. Diabetic dogs referred for cataract surgery at DVS frequently have poorly controlled diabetes mellitus as assessed by clinical signs, serum fructosamine, and serial blood glucose analysis. The stress of hospitalization in the immediate preoperative period may further exacerbate diabetic instability resulting in marked preoperative and intraoperative hyperglycemia.16 At plasma glucose levels above approximately 9.9?mmol/L (180?mg/dL) the glucose load filtered by the kidneys exceeds the renal tubular capacity for reabsorption.