Routine Care For Crohn's Disease In Children Should Include Measurement Of Bone Age
One of our findings that surprised me was that 41 percent of our patients had BA-Z scores that were less than -2. I did not expect that such a large proportion of patients would have this degree of delay, said Gupta. Crohns disease is a chronic disorder characterized by inflammation in the gastrointestinal tract. It is one of the two main disease subcategories of inflammatory bowel disease, along with ulcerative colitis. About one quarter of the more than one million Americans with inflammatory bowel disease are diagnosed in childhood and adolescence. In pediatric patients, the inflammation characteristic of the disease may lead to an inability to grow normally. Poor growth may be the only presenting sign of Crohns disease in children and adolescents. Facts on Pediatric Crohns Disease About one quarter of the more than one million Americans with inflammatory bowel disease are diagnosed in childhood and adolescence. Up to 80 percent of patients show compromised growth Common symptoms include stomach pain, fever, weight loss, fatigue, diarrhea and poor growth. Crohns sufferers can also have certain types of skin lesions, liver problems, eye abnormalities and arthritis due to the underlying inflammatory process. The disease is marked by an abnormal response by the bodys immune system. The cause is not well understood but probably has a genetic component and an unknown trigger, according to the researchers. The interpretation of a patients growth changes when his or her bone age, rather than just chronological age, is taken into consideration. The added information is also useful for properly interpreting height increments following therapeutic interventions. We need further studies to understand the effects of disease activity on bone age advancement and to determine which patients require more frequent monitoring of bone age, Gupta said. continue reading this http://www.ucsf.edu/news/2012/05/12067/routine-care-crohns-disease-children-should-include-measurement-bone-age
Crohn's Disease in Children
It is a chronic condition that may recur at various times over a lifetime. It usually involves the small intestine, most often the lower part called the ileum. However, inflammation may also affect the entire digestive tract, including the mouth, esophagus, stomach, duodenum, appendix, or anus. Click Image to Enlarge What causes Crohn's disease? There are many theories regarding Crohn's disease, but none have been proven. One theory suggests that some agent, perhaps a virus or bacteria, affects the body's immune system and triggers an inflammatory reaction in the intestinal wall. Although there is a lot of evidence that patients with this disease have abnormalities of the immune system, it is not known whether the immune problems are a cause or a result of the disease. Who is affected by Crohn's disease? While Crohn's disease may affect persons of all ages, the age group most often affected isA15Ato 35 years. However, Crohn's may be seen in young children. Males and females are affected equally. It appears to run in some families, with about 20 percent of people with Crohn's disease having a blood relative with some form of inflammatory bowel disease. In those who have a family history, it is very likely that Crohn's disease will begin in the teens and twenties. What are the symptoms of Crohn's disease? this link http://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=90&ContentID=P01987
Crohn's Disease in Children
It is a chronic condition that may recur at various times over a lifetime. It usually involves the small intestine, most often the lower part called the ileum. However, inflammation may also affect the entire digestive tract, including the mouth, esophagus, stomach, duodenum, appendix, or anus. Click Image to Enlarge What causes Crohn's disease? There are many theories regarding Crohn's disease, but none have been proven. One theory suggests that some agent, perhaps a virus or bacteria, affects the body's immune system and triggers an inflammatory reaction in the intestinal wall. Although there is a lot of evidence that patients with this disease have abnormalities of the immune system, it is not known whether the immune problems are a cause or a result of the disease. Who is affected by Crohn's disease? While Crohn's disease may affect persons of all ages, the age group most often affected isA15Ato 35 years. However, Crohn's may be seen in young children. Males and females are affected equally. It appears to run in some families, with about 20 percent of people with Crohn's disease having a blood relative with some form of inflammatory bowel disease. In those who have a family history, it is very likely that Crohn's disease will begin in the teens and twenties. What are the symptoms of Crohn's disease? this link http://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=90&ContentID=P01987
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