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RAP and AMIO significantly decreased CFR (baseline = 100%) when compared with any other group (RAP:57 �� 11%; RAP + AMIO:54 �� 18% vs Sham:103 �� 14% vs RAP + DRO:96 �� 13% vs DRO:110 �� 17%; p http://www.selleckchem.com/products/cb-5083.html effects in coronary arteries and improved microcirculation, thus abolishing RAP-induced microvascular flow disturbances. P006 CONVERSION EFFICACY OF PROPAPHENONE IBOUTILIDE AND AMIODARONE IN MEN AND WOMEN WITH PAROXYSMAL ATRIAL FIBRILLATION OF RECENT ONSET Panageas V; Zika A General Hospital of Pyrgos Introduction: We aimed to determine whether the efficacy of antiarrhythmic agents is associated with sex, in patients with Paroxysmal Atrial Fibrillation of 3�C48h. duration (PAFib). Methods used: We have observed 94 patients (64 men and 30 women). with PAFib. Patients were treated with Propaphenone (PR.), Ibutilide (IB) or Amiodarone (AMIO). If sinus rhythm was not restored with the first drug we used another one. Successful cardioversion was defined as arrhythmia termination within 48 hours. The results were analysed using Fisher's exact test. Summary http://www.selleckchem.com/products/a-1155463.html of Results: Of 94 patients 89 were restored (95%). 60 men (93,75%) and 29 women (96,77%) were restored (p-value = 1). As regards Propaphenone we used it as a 1st choice in 32 men (efficacy: 81,25%) and in 15 women (efficacy: 93,34%)(p = 0,6599). Propaphenone was never used as a 2nd choice). Amiodarone was used in 21 men as a 1st choice, with 90,5% efficacy and in 4 men as a 2nd choice, with 75% efficacy. In women it was used only as a 1st choice in 5 cases with 80% efficacy. (Amiodarone: p = 0,5153 as a first choice and 1,0000 as a 2nd choice). Finally, Iboutilide was used http://www.selleck.cn/products/PD-0332991.html in 11 men and 10 women as a first choice and in 4 men and 1 women as a 2nd choice with efficacy 100% (in all of theme) (so p = 1,0000). Conclusions: In Southern-West Greece the association between the gender and the conversion rate of antiarrhythmic drugs is not statistically significant. P007 ATRIAL EXCITATION PATTERNS OF REFRACTORY AND NON REFRACTORY TO PROPAPHENONE RECURRENT PAROXYSMAL ATRIAL FIBRILLATION Dakos G; Vassilikos V; Chouvarda I; Chatzizisis I; Mantziari L; Kamberidis V; Paraskevaidis S; Tsilonis K; Maglaveras N; Styliadis I 1st Cardiology Dept., Aristotle University of Thessaloniki, Greece The aim of this study was to associate the effects of propaphenone on the atrial excitation patterns of the recurrent paroxysmal atrial fibrillation (PAF), with P wave wavelet analysis.