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Magn Reson Med 63:1098�C1103, 2010. ? 2010 Wiley-Liss, Inc. ""To demonstrate the feasibility of accelerating measurements of cardiac fiber structure using simultaneous multislice (SMS) imaging. SMS excitation with a blipped http://www.selleckchem.com/products/epacadostat-incb024360.html controlled aliasing (CAIPI) readout was incorporated into a diffusion-encoded stimulated echo pulse sequence to obtain diffusion measurements in three separate slices of the heart (8-mm thickness, 12-mm gap). A novel image entropy-based method for removing image ghosts in blipped CAIPI acquisitions is also introduced that enables SMS imaging of closely spaced slices in the heart. The average retained signal-to-noise ratio (SNR) using this acquisition scheme is 70%?��?5%, higher than the standard ?=?57% SNR penalty with three-fold acceleration. No significant difference was observed in the apparent diffusion coefficient and helix angle diffusion parameters between a time-equivalent conventional single-slice scan and the three-fold accelerated SMS acquisition. A 10% mean bias was observed in fractional http://www.selleckchem.com/products/MG132.html anisotropy between single-slice and SMS acquisitions. The new sequence was used to obtain high-quality diffusion measurements in three closely spaced cardiac slices in a clinically feasible nine breath-hold examination. The accelerated multiband sequence is anticipated to improve quantitative measurements of cardiac microstructure by reducing the number of breath-holds required for the scan, making it practical to incorporate diffusion tensor measurements within a comprehensive clinical examination. Magn Reson Med, 2014. ? 2014 Wiley Periodicals, Inc. ""We propose a compressed-sensing (CS) technique based on magnitude image subtraction for high spatial and temporal resolution dynamic contrast-enhanced MR angiography (CE-MRA). Our technique integrates the magnitude difference image into the CS reconstruction to promote subtraction sparsity. Fully sampled Cartesian 3D CE-MRA datasets from 6 volunteers were retrospectively under-sampled and three reconstruction strategies were evaluated: k-space subtraction CS, independent CS, and magnitude subtraction CS. The techniques were compared in image quality (vessel delineation, image artifacts, and noise) and image reconstruction error. Our CS technique was further tested on seven volunteers using a prospectively under-sampled CE-MRA sequence. Compared http://www.selleck.cn/products/pfi-2.html with k-space subtraction and independent CS, our magnitude subtraction CS provides significantly better vessel delineation and less noise at 4�� acceleration, and significantly less reconstruction error at 4�� and 8�� (P?